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Molecular Biology of the Parathyroid - nouveau livre
ISBN: 9781441934154
aintaining extracellular calcium concentrations within a narrow range is critical for the survival of most vertebrates. PTH, together with vitamin D, responds to hypocalcemia to increase … Plus…
aintaining extracellular calcium concentrations within a narrow range is critical for the survival of most vertebrates. PTH, together with vitamin D, responds to hypocalcemia to increase extracellu M lar calcium levels, by acting on bone, kidney and intestine. The recent intro duction of PTH as a major therapeutic agent in osteoporosis has directed renewed interest in this important hormone and in the physiology of the parathyroid gland. The parathyroid is unique in that low serum calcium stimulates PTH secretion. As hypocalcemia persists, there is also an increase in PTH synthesis. Chronic hypocalcemia leads to hypertrophy and hyper plasia of the parathyroid gland together with increased production of the hormone. Phosphate is also a key modulator of PTH secretion, gene expres sion and parathyroid cell proliferation. Understanding the biology of the parathyroid as well as the mecha nisms of associated diseases has taken great strides in recent years. This book summarizes the molecular mechanisms involved in the function of the para thyroid gland. The first chapter reviews the development of the parathyroid gland and the genes involved in this process as identified using genetically manipulated mice. Then the biosynthetic pathway of PTH from gene ex pression to its intracellular processing and the sequences in the gene control ling its transcription as well as those regulating mRNA processing, stability and translation are described. Books > Health > Medical > Biochemistry List_Books, [PU: Springer]<
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Molecular Biology of the Parathyroid - nouveau livre
ISBN: 9781441934154
aintaining extracellular calcium concentrations within a narrow range is critical for the survival of most vertebrates. PTH, together with vitamin D, responds to hypocalcemia to increase … Plus…
aintaining extracellular calcium concentrations within a narrow range is critical for the survival of most vertebrates. PTH, together with vitamin D, responds to hypocalcemia to increase extracellu M lar calcium levels, by acting on bone, kidney and intestine. The recent intro duction of PTH as a major therapeutic agent in osteoporosis has directed renewed interest in this important hormone and in the physiology of the parathyroid gland. The parathyroid is unique in that low serum calcium stimulates PTH secretion. As hypocalcemia persists, there is also an increase in PTH synthesis. Chronic hypocalcemia leads to hypertrophy and hyper plasia of the parathyroid gland together with increased production of the hormone. Phosphate is also a key modulator of PTH secretion, gene expres sion and parathyroid cell proliferation. Understanding the biology of the parathyroid as well as the mecha nisms of associated diseases has taken great strides in recent years. This book summarizes the molecular mechanisms involved in the function of the para thyroid gland. The first chapter reviews the development of the parathyroid gland and the genes involved in this process as identified using genetically manipulated mice. Then the biosynthetic pathway of PTH from gene ex pression to its intracellular processing and the sequences in the gene control ling its transcription as well as those regulating mRNA processing, stability and translation are described. Books List_Books, [PU: Springer]<
Indigo.ca
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Tally Naveh-Many: Molecular Biology of the Parathyroid - Livres de poche
ISBN: 9781441934154
Paperback, [PU: Springer-Verlag New York Inc.], The recent intro duction of PTH as a major therapeutic agent in osteoporosis has directed renewed interest in this important hormone and i… Plus…
Paperback, [PU: Springer-Verlag New York Inc.], The recent intro duction of PTH as a major therapeutic agent in osteoporosis has directed renewed interest in this important hormone and in the physiology of the parathyroid gland., Medical Research<
Molecular Biology of the Parathyroid - nouveau livre
ISBN: 9781441934154
aintaining extracellular calcium concentrations within a narrow range is critical for the survival of most vertebrates. PTH, together with vitamin D, responds to hypocalcemia to increase … Plus…
aintaining extracellular calcium concentrations within a narrow range is critical for the survival of most vertebrates. PTH, together with vitamin D, responds to hypocalcemia to increase extracellu M lar calcium levels, by acting on bone, kidney and intestine. The recent intro duction of PTH as a major therapeutic agent in osteoporosis has directed renewed interest in this important hormone and in the physiology of the parathyroid gland. The parathyroid is unique in that low serum calcium stimulates PTH secretion. As hypocalcemia persists, there is also an increase in PTH synthesis. Chronic hypocalcemia leads to hypertrophy and hyper plasia of the parathyroid gland together with increased production of the hormone. Phosphate is also a key modulator of PTH secretion, gene expres sion and parathyroid cell proliferation. Understanding the biology of the parathyroid as well as the mecha nisms of associated diseases has taken great strides in recent years. This book summarizes the molecular mechanisms involved in the function of the para thyroid gland. The first chapter reviews the development of the parathyroid gland and the genes involved in this process as identified using genetically manipulated mice. Then the biosynthetic pathway of PTH from gene ex pression to its intracellular processing and the sequences in the gene control ling its transcription as well as those regulating mRNA processing, stability and translation are described. Books > Health > Medical > Biochemistry List_Books, [PU: Springer]<
new in stock. Frais d'envoizzgl. Versandkosten., Livraison non-comprise
Molecular Biology of the Parathyroid - nouveau livre
ISBN: 9781441934154
aintaining extracellular calcium concentrations within a narrow range is critical for the survival of most vertebrates. PTH, together with vitamin D, responds to hypocalcemia to increase … Plus…
aintaining extracellular calcium concentrations within a narrow range is critical for the survival of most vertebrates. PTH, together with vitamin D, responds to hypocalcemia to increase extracellu M lar calcium levels, by acting on bone, kidney and intestine. The recent intro duction of PTH as a major therapeutic agent in osteoporosis has directed renewed interest in this important hormone and in the physiology of the parathyroid gland. The parathyroid is unique in that low serum calcium stimulates PTH secretion. As hypocalcemia persists, there is also an increase in PTH synthesis. Chronic hypocalcemia leads to hypertrophy and hyper plasia of the parathyroid gland together with increased production of the hormone. Phosphate is also a key modulator of PTH secretion, gene expres sion and parathyroid cell proliferation. Understanding the biology of the parathyroid as well as the mecha nisms of associated diseases has taken great strides in recent years. This book summarizes the molecular mechanisms involved in the function of the para thyroid gland. The first chapter reviews the development of the parathyroid gland and the genes involved in this process as identified using genetically manipulated mice. Then the biosynthetic pathway of PTH from gene ex pression to its intracellular processing and the sequences in the gene control ling its transcription as well as those regulating mRNA processing, stability and translation are described. Books List_Books, [PU: Springer]<
new in stock. Frais d'envoizzgl. Versandkosten., Livraison non-comprise
Tally Naveh-Many: Molecular Biology of the Parathyroid - Livres de poche
ISBN: 9781441934154
Paperback, [PU: Springer-Verlag New York Inc.], The recent intro duction of PTH as a major therapeutic agent in osteoporosis has directed renewed interest in this important hormone and i… Plus…
Paperback, [PU: Springer-Verlag New York Inc.], The recent intro duction of PTH as a major therapeutic agent in osteoporosis has directed renewed interest in this important hormone and in the physiology of the parathyroid gland., Medical Research<
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Données bibliographiques du meilleur livre correspondant
The unraveling of the biology and disease mechanisms of the parathyroid has taken great strides in the recent few years. Parathyroid molecular biology is the first book to describe recent studies and discoveries in the field in detail. Key topics addressed include:The study of the molecular biology of the parathyroid hormone gene and its regulation by calcium, phosphate, and vitamin DThe generation of mice with genetic deletions of the parathyroid, as well as mice which fail to develop the parathyroid glandThe parathyroid's connection to the calcium receptor and its effects, such as regulation of PTH secretion, gene expression, and proliferationThe genetic mutations leading to diseases of decreased or excessive activity of the parathyroid The mechanisms of actions associated with patients with chronic renal failure and the development of markedly excessive activity of the parathyroid that causes severe bone diseaseThis book will be essential reading to everyone interested in the latest developments in this burgeoning field.
Informations détaillées sur le livre - Molecular Biology of the Parathyroid
EAN (ISBN-13): 9781441934154 ISBN (ISBN-10): 1441934154 Version reliée Livre de poche Date de parution: 2010 Editeur: Springer-Verlag GmbH 216 Pages Poids: 0,334 kg Langue: eng/Englisch
Livre dans la base de données depuis 2011-11-23T10:21:46+01:00 (Paris) Page de détail modifiée en dernier sur 2023-11-24T19:05:46+01:00 (Paris) ISBN/EAN: 9781441934154
ISBN - Autres types d'écriture: 1-4419-3415-4, 978-1-4419-3415-4 Autres types d'écriture et termes associés: Auteur du livre: many, tally
Données de l'éditeur
Auteur: Tally Naveh-Many Titre: Molecular Biology Intelligence Unit; Molecular Biology of the Parathyroid Editeur: Springer; Springer US 199 Pages Date de parution: 2010-12-06 New York; NY; US Imprimé / Fabriqué en Langue: Anglais 160,49 € (DE) 164,99 € (AT) 177,00 CHF (CH) POD XIV, 199 p. 71 illus., 5 illus. in color.
Development of Parathyroid Glands.- Parathyroid Hormone, from Gene to Protein.- Toward an Understanding of Human Parathyroid Hormone Structure and Function.- The Calcium Sensing Receptor.- Regulation of Parathyroid Hormone mRNA Stability by Calcium and Phosphate.- In Silico Analysis of Regulatory Sequences in the Human Parathyroid Hormone Gene.- Regulation of Parathyroid Hormone Gene Expression by 1,25-Dihydroxyvitamin D.- Vitamin D Analogs for the Treatment of Secondary Hyperparathyroidism in Chronic Renal Failure.- Parathyroid Gland Hyperplasia in Renal Failure.- Molecular Mechanisms in Parathyroid Tumorigenesis.- Molecular Genetic Abnormalities in Sporadic Hyperparathyroidism.- Genetic Causes of Hypoparathyroidism.- Skeletal and Reproductive Abnormalities in Pth-Null Mice. Molecular Biology of the Parathyroid is the first book to describe recent studies and discoveries in the field in detail. This title is essention reading for enocrinologists and all researchers working in the field of bone and mineral research. Includes supplementary material: sn.pub/extras
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