ISBN: 9780471042136

On the cover of this book is a Pacific yew tree, found in the ancient forests of the Pacific Northwest. The bark of the Pacific yew tree produces Taxol, found to be a highly effective dru… Plus…

On the cover of this book is a Pacific yew tree, found in the ancient forests of the Pacific Northwest. The bark of the Pacific yew tree produces Taxol, found to be a highly effective drug against ovarian and breast cancer. Taxol blocks mitosis during eukaryotic cell division. The supply of Taxol from the Pacific yew tree is vanishingly small, however. A single 100-year-old tree provides only about one dose of the drug (roughly 300 mg). For this reason, as well as the spectacular molecular architecture of Taxol, synthetic organic chemists fiercely undertook efforts to synthesize it. Five total syntheses of Taxol have thus far been reported. Now, a combination of isolation of a related metabolite from European yew needles, and synthesis of Taxol from that intermediate, supply the clinical demand. This case clearly demonstrates the importance of synthesis and the use of organic chemistry. It's just one of the many examples used in the text that will spark the interest of students and get them involved in the study of organic chemistry! Media > Book, [PU: Wiley]<

2000, ISBN: 9780471042136

John Wiley & Sons, 1980. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In fair condition, suitable as a study co… Plus…

John Wiley & Sons, 1980. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In fair condition, suitable as a study copy. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,2000grams, ISBN:0471042137, John Wiley & Sons, 1980, 0<

1980, ISBN: 9780471042136

PAPERBACK, Gebraucht, guter Zustand, 0471042137 Good condition with normal wear. Supplemental materials such as CDs or access codes may NOT be included regardless of title. May have books… Plus…

PAPERBACK, Gebraucht, guter Zustand, 0471042137 Good condition with normal wear. Supplemental materials such as CDs or access codes may NOT be included regardless of title. May have bookstore stickers on cover. Expedited shipping available (2-4 day delivery)! Contact us with any questions!, [PU: Wiley]<