Cytochrome P450 - nouveau livre

Livre dans la base de données depuis 2015-10-25T19:32:45+01:00 (Paris)
Page de détail modifiée en dernier sur 2023-03-23T20:40:03+01:00 (Paris)
ISBN/EAN: 9783319121086

ISBN - Autres types d'écriture:
978-3-319-12108-6
Autres types d'écriture et termes associés:
Titre du livre: cytochrome p450

Données de l'éditeur

Auteur: Paul R. Ortiz de Montellano
Titre: Cytochrome P450 - Structure, Mechanism, and Biochemistry
Editeur: Springer; Springer International Publishing
912 Pages
Date de parution: 2015-03-13
Cham; CH
Imprimé / Fabriqué en
Langue: Anglais
416,23 € (DE)
427,90 € (AT)
472,00 CHF (CH)
Available
X, 912 p. 243 illus., 80 illus. in color.

EA; E107; eBook; Nonbooks, PBS / Medizin/Pharmazie; Pharmazie, Apotheke; Verstehen; Cytochrome P450; drug metabolism; enzyme mechanism; hemoprotein function; lipid metabolism; protein structure; sterol biogenesis; B; Pharmacy; Biochemistry, general; Pharmacology/Toxicology; Pharmacy; Biochemistry; Pharmacology; Medicine; Biochemie; Pharmakologie; BB

This authoritative Fourth Edition summarizes the advances of the past decade concerning the structure, mechanism, and biochemistry of cytochrome P450 enzymes, with sufficient coverage of earlier work to make each chapter a comprehensive review of the field. Thirteen chapters are divided into two detailed volumes, the first covering the fundamentals of cytochrome P450 biochemistry, as well as the microbial, plant, and insect systems, and the second exclusively focusing on mammalian systems.

is a key resource for scientists, professors, and students interested in fields as diverse as biochemistry, chemistry, biophysics, molecular biology, pharmacology and toxicology.

.- Volume 1

.- 1 Structures of Cytochrome P450 Enzymes

.- 2 Electron Transfer Partners of Cytochrome P450

.- 3 Activation of Molecular Oxygen in Cytochromes P450

.- 4 Substrate Oxidation by Cytochrome P450 Enzymes

.- 5 Inhibition of Cytochrome P450 Enzymes

.- 6 Microbial Cytochromes P450

.- 7 P450s in Plants, Insects and their Fungal Pathogens

.- 8 P450 Biotechnology

.- Volume 2

.- 9 Human Cytochrome P450 Enzymes

.- 10 Nuclear Receptor-Mediated Regulation of Cytochrome P450 Genes

.- 11 Hormonal Regulation of Liver Cytochrome P450 Enzymes

.- 12 P450 Enzymes in Steroid Processing

.- 13 P450 Enzymes in Lipid Oxidation.

received his PhD in bioorganic chemistry from Harvard University, Cambridge, MA. After postdoctoral work as a North Atlantic Treaty Organization Fellow in Zürich, Switzerland, and a stint with Syntex in Mexico City and Palo Alto, California, he joined the faculty of the University of California in San Francisco, where he is currently Professor, Vice-chair of the Department of Pharmaceutical Chemistry, and Associate Dean for Research of the School of Pharmacy. His research interests center on the structure, mechanism, inhibition, and biochemistry of hemoproteins, including the cytochrome P450 enzymes. He has received the B.B. Brodie Award in Drug Metabolism from the American Society of Pharmacology and Experimental Therapeutics, the R.T. Williams Distinguished Scientific Achievement Award from the International Society for the Study of Xenobiotics, and the Ernest H. Volwiler Research Achievement Award from the American Association of Colleges of Pharmacy.

This authoritative Fourth Edition summarizes the advances of the past decade concerning the structure, mechanism, and biochemistry of cytochrome P450 enzymes, with sufficient coverage of earlier work to make each chapter a comprehensive review of the field. Thirteen chapters are divided into two detailed volumes, the first covering the fundamentals of cytochrome P450 biochemistry, as well as the microbial, plant, and insect systems, and the second exclusively focusing on mammalian systems.

is a key resource for scientists, professors, and students interested in fields as diverse as biochemistry, chemistry, biophysics, molecular biology, pharmacology and toxicology.

Two-volume Fourth Edition updated with the most cutting-edge research

Explores the advances of the past decade on the structure, mechanism, and biochemistry of cytochrome P450 enzymes

Discusses structure and role of cytochrome P450 in biology

Includes supplementary material: sn.pub/extras