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Single-Stranded DNA Binding Proteins: Methods and Protocols (Methods in Molecular Biology) - James L. Keck
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James L. Keck:
Single-Stranded DNA Binding Proteins: Methods and Protocols (Methods in Molecular Biology) - edition reliée, livre de poche

ISBN: 162703031X

[SR: 5955025], Hardcover, [EAN: 9781627030311], Humana Press, Humana Press, Book, [PU: Humana Press], Humana Press, The genomes of cellular organisms are organized as double-stranded DNA, a structure that must be unwound to provide DNA replication, recombination, and repair machinery access to genomic information.  However, DNA unwinding comes with inherent risks to genome stability.  To help mediate these risks, bacterial, archael, and eukaryotic cells have evolved protective ssDNA-binding proteins (SSBs) that bind ssDNA with high affinity and specificity.  SSBs also aid genome metabolic processes through direct interactions with key proteins in genome maintenance enzymes.  Single-Stranded DNA Binding Proteins: Methods and Protocols assembles methods developed for examining the fundamental properties of SSBs and for exploiting the biochemical functions of SSBs for their use as in vitro and in vivo reagents. Clearly and concisely organized, the volume opens with an introduction to the structures and functions of SSBs, followed protocols for studying SSB/DNA complexes, methods for studying SSB/heterologous protein complexes, protocols for interrogating post-translational modifications of SSBs, and concludes with uses of fluorescently-labeled SSBs for in vitro and in vivo studies of genome maintenance processes.  Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.Authoritative and easily accessible, Single-Stranded DNA Binding Proteins: Methods and Protocols provides a rich introduction for investigators who are interested in this fascinating family of DNA-binding proteins., 13511, Biochemistry, 13469, Biological Sciences, 75, Science & Math, 1000, Subjects, 283155, Books, 491702, Biology & Life Sciences, 491704, Anatomy & Physiology, 684289011, Biology, 491716, Botany, 491708, Ecology, 491714, Zoology, 468216, Science & Mathematics, 465600, New, Used & Rental Textbooks, 2349030011, Specialty Boutique, 283155, Books

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Single-Stranded DNA Binding Proteins - James L. Keck
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James L. Keck:
Single-Stranded DNA Binding Proteins - nouveau livre

2012, ISBN: 162703031X

ID: 8924193828

[EAN: 9781627030311], Neubuch, [SC: 0.0], [PU: Springer-Verlag Gmbh Sep 2012], EIWEISS (CHEMISCH); PROTEIN, Neuware - The genomes of cellular organisms are organized as double-stranded DNA, a structure that must be unwound to provide DNA replication, recombination, and repair machinery access to genomic information. However, DNA unwinding comes with inherent risks to genome stability. To help mediate these risks, bacterial, archael, and eukaryotic cells have evolved protective ssDNA-binding proteins (SSBs) that bind ssDNA with high affinity and specificity. SSBs also aid genome metabolic processes through direct interactions with key proteins in genome maintenance enzymes. Single-Stranded DNA Binding Proteins: Methods and Protocols assembles methods developed for examining the fundamental properties of SSBs and for exploiting the biochemical functions of SSBs for their use as in vitro and in vivo reagents. Clearly and concisely organized, the volume opens with an introduction to the structures and functions of SSBs, followed protocols for studying SSB/DNA complexes, methods for studying SSB/heterologous protein complexes, protocols for interrogating post-translational modifications of SSBs, and concludes with uses of fluorescently-labeled SSBs for in vitro and in vivo studies of genome maintenance processes. Written in the successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. 259 pp. Englisch

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Single-Stranded DNA Binding Proteins. - Keck, James L. (Ed.)
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Keck, James L. (Ed.):
Single-Stranded DNA Binding Proteins. - edition reliée, livre de poche

2012, ISBN: 162703031X

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[EAN: 9781627030311], [SC: 3.0], [PU: New York, Springer, 2012.], Methods and Protocols. X, 259 p. Hardcover. Stamped. Methods in Molecular Biology 932.

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Single-stranded DNA Binding Proteins - James L. Keck
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James L. Keck:
Single-stranded DNA Binding Proteins - edition reliée, livre de poche

2012, ISBN: 9781627030311

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Single-Stranded DNA Binding Proteins - Keck, James L. (EDT)
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Keck, James L. (EDT):
Single-Stranded DNA Binding Proteins - nouveau livre

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ID: 162703031X

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Détails sur le livre
Single-Stranded DNA Binding Proteins: Methods and Protocols (Methods in Molecular Biology)
Auteur:

James L. Keck

Titre:

Single-Stranded DNA Binding Proteins: Methods and Protocols (Methods in Molecular Biology)

ISBN:

Informations détaillées sur le livre - Single-Stranded DNA Binding Proteins: Methods and Protocols (Methods in Molecular Biology)


EAN (ISBN-13): 9781627030311
ISBN (ISBN-10): 162703031X
Version reliée
Date de parution: 2012
Editeur: Springer-Verlag GmbH
259 Pages
Poids: 0,680 kg
Langue: Englisch

Livre dans la base de données depuis 16.11.2007 12:02:35
Livre trouvé récemment le 27.05.2017 08:50:01
ISBN/EAN: 9781627030311

ISBN - Autres types d'écriture:
1-62703-031-X, 978-1-62703-031-1


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