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The Evaluation of Surrogate Endpoints - Tomasz Burzykowski
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Tomasz Burzykowski:
The Evaluation of Surrogate Endpoints - Livres de poche

2010, ISBN: 1441919066

ID: 9612480430

[EAN: 9781441919069], Neubuch, [PU: Springer Nov 2010], This item is printed on demand - Print on Demand Titel. - Covers the latest research on a sensitive and controversial topic in a professional and well researched manner. Provides practical outlook as well as model guidelines and software tools that should be of interest to people who use the software tools described and those who do not. Related title by Co-author Geert Molenbergh has sold more than 3500 copies world wide. Provides dual viewpoints: from scientists in the industry as well as regulatory authorities.Both humanitarian and commercial considerations have spurred intensive search for methods to reduce the time and cost required to develop new therapies. The identification and use of surrogate endpoints, i.e., measures that can replace or supplement other endpoints in evaluations of experimental treatments or other interventions, is a general strategy that has stimulated both enthusiasm and skepticism. Surrogate endpoints are useful when they can be measured earlier, more conveniently, or more frequently than the 'true' endpoints of primary interest. Regulatory agencies around the globe, particularly in the United States, Europe, and Japan, are introducing provisions and policies relating to the use of surrogate endpoints in registration studies. But how can one establish the adequacy of a surrogate What kind of evidence is needed, and what statistical methods portray that evidence most appropriately This book offers a balanced account on this controversial topic. The text presents major developments of the last couple of decades, together with a unified, meta-analytic framework within which surrogates can be evaluated from several angles. Methodological development is coupled with perspectives on various therapeutic areas. Academic views are juxtaposed with standpoints of scientists working in the biopharmaceutical industry as well as of colleagues from the regulatory authorities. Tomasz Burzykowski is Assistant Professor of Biostatistics at the Limburgs Universitair Centrum in Belgium. Dr. Burzykowski has published methodological work on the analysis of survey data, meta-analyses of clinical trials, and validation of surrogate endpoints. He is a co-author of numerous papers applying statistical methods to clinical data in different disease areas (cancer, cardiovascular diseases, dermatology, orthodontics). Geert Molenberghs is Professor of Biostatistics at the Limburgs Universitair Centrum in Belgium. Dr. Molenberghs published methodological work on surrogate markers in clinical trials, categorical data, longitudinal data analysis, and on the analysis of non-response in clinical and epidemiological studies. He serves as Joint Editor for Applied Statistics (2001-2004) and is President of the International Biometric Society (2004-2005). He was elected Fellow of the American Statistical Association and received the Guy Medal in Bronze from the Royal Statistical Society. Marc Buyse founded the International Drug Development Institute in 1991. He is Past President of the International Society for Clinical Biostatistics, Past President of the Quetelet Society, and Past Board Member of the Society for Clinical Trials. He is currently the Executive Director of IDDI (International Drug Development Institute) and Associate Professor of biostatistics at the Limburgs Universitair Centrum, Center for Statistics, Diepenbeek, Belgium. He has published extensively in the fields of biostatistics and oncology. His research interests include meta-analysis, surrogate endpoints, statistical detection of fraud, and the design and statistical analysis of clinical trials. 436 pp. Englisch

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The Evaluation of Surrogate Endpoints - Herausgegeben von Burzykowski, Tomasz Molenberghs, Geert Buyse, Marc
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Herausgegeben von Burzykowski, Tomasz Molenberghs, Geert Buyse, Marc:
The Evaluation of Surrogate Endpoints - Livres de poche

2010, ISBN: 9781441919069

Edition reliée

[ED: Softcover], [PU: Springer, Berlin], PCovers the latest research on a sensitive and controversial topic in a professional and well researched manner./P PProvides practical outlook as well as model guidelines and software tools that should be of interest to people who use the software tools described and those who do not./P PRelated title by Co-author Geert Molenbergh has sold more than 3500 copies world wide./P PProvides dual viewpoints: from scientists in the industry as well as regulatory authorities./PSoftcover reprint of hardcover 1st ed. 2005. 2010. xxiv, 410 S. 235 mmVersandfertig in 3-5 Tagen, [SC: 0.00]

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The Evaluation of Surrogate Endpoints (Statistics for Biology and Health) - Tomasz Burzykowski, Geert Molenberghs, Marc Buyse
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Tomasz Burzykowski, Geert Molenberghs, Marc Buyse:
The Evaluation of Surrogate Endpoints (Statistics for Biology and Health) - Livres de poche

ISBN: 1441919066

[SR: 992458], Taschenbuch, [EAN: 9781441919069], Springer, Springer, Book, [PU: Springer], Springer, 56659011, Forschung, 56535011, Medizin, 54071011, Genres, 52044011, Fremdsprachige Bücher, 56708011, Pathologie, 56698011, Fachgebiete, 56535011, Medizin, 54071011, Genres, 52044011, Fremdsprachige Bücher

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The Evaluation of Surrogate Endpoints (Statistics for Biology and Health)
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The Evaluation of Surrogate Endpoints (Statistics for Biology and Health) - Livres de poche

2010, ISBN: 1441919066

ID: 19403569180

[EAN: 9781441919069], Neubuch, [PU: Springer], This item is printed on demand for shipment within 3 working days.

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Evaluation of Surrogate Endpoints - Tomasz Burzykowski; Geert Molenberghs; Marc Buyse
Livre non disponible
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Tomasz Burzykowski; Geert Molenberghs; Marc Buyse:
Evaluation of Surrogate Endpoints - Livres de poche

2010, ISBN: 9781441919069

Edition reliée, ID: 16197517

Softcover reprint of hardcover 1st ed. 2005, Softcover, Buch, [PU: Springer-Verlag New York Inc.]

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Détails sur le livre
The Evaluation of Surrogate Endpoints
Auteur:

Herausgegeben von Burzykowski, Tomasz Molenberghs, Geert Buyse, Marc

Titre:

The Evaluation of Surrogate Endpoints

ISBN:

Covers the latest research on a sensitive and controversial topic in a professional and well researched manner.Provides practical outlook as well as model guidelines and software tools that should be of interest to people who use the software tools described and those who do not.Related title by Co-author Geert Molenbergh has sold more than 3500 copies world wide.Provides dual viewpoints: from scientists in the industry as well as regulatory authorities.

Informations détaillées sur le livre - The Evaluation of Surrogate Endpoints


EAN (ISBN-13): 9781441919069
ISBN (ISBN-10): 1441919066
Version reliée
Livre de poche
Date de parution: 2010
Editeur: Springer-Verlag GmbH
436 Pages
Poids: 0,655 kg
Langue: eng/Englisch

Livre dans la base de données depuis 22.09.2010 20:31:28
Livre trouvé récemment le 06.07.2016 21:37:44
ISBN/EAN: 9781441919069

ISBN - Autres types d'écriture:
1-4419-1906-6, 978-1-4419-1906-9


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