2018, ISBN: 1331181828

[EAN: 9781331181828], Libro nuovo, [SC: 0.57], [PU: Forgotten Books], Language: English . Brand New Book ***** Print on Demand *****. Excerpt from International Clinics, Vol. 4: A Quarter… Plus…

[EAN: 9781331181828], Libro nuovo, [SC: 0.57], [PU: Forgotten Books], Language: English . Brand New Book ***** Print on Demand *****. Excerpt from International Clinics, Vol. 4: A Quarterly of Illustrated Clinical Lectures and Especially Prepared Original Articles on Treatment, Medicine, Surgery, Neurology, Paediatrics, Obstetrics, Gynaecology, Orthopaedics, Pathology, Dermatology, Ophthalmology, Otology, Rhinology, Laryngology, Hyg The antimeningitis serum, being of the general nature of an anti-endotoxic serum, is not subject to standardization according to the methods employed with the antitoxic sera. The antimeningitis serum possesses, it is true, a certain but definite neutralizing power for the autolysate, but this property cannot be used for pur poses of titration. The anti-endotoxic strength of the serum is probably not a correct measure of its therapeutic value since it is not a measure of other immunity principles contained within the serum, whose action is very important. Moreover, the autolysate does not act in a uniform manner upon young guinea-pigs and mice, which are, on the whole, the laboratory animals most susceptible to its toxic effects. Whether introduced beneath the Skin, into the peri toneal cavity, or, as tested by J Obling, by intracardiac injection, the fatal dose ?uctuates greatly in guinea-pigs of 200 grammes weight. The employment of living cultures of the meningococcus for purposes of standardization of the serum is also excluded, by reason of their highly variable pathogenicity, for mice, guinea-pigs and other animals. Nor do we possess at present any means by which the pathogenic properties of the living cultures can be main tained at a fixed and suiciently high level. Moreover, no fixed relation exists between the complement-binding power of the anti serum and its therapeutic activity, and hence this method of titra tion, introduced by Kolle and Wassermann, has had to be aban doned. On the other hand, it now seems not improbable that in the opsonins or bacteriotropins we possesses a measure of the thera peutie activity of the antimeningitis serum. It is not to be supposed that the activity of the antiserum resides Wholly in the opsonins, but it is probable that they are a measure of other useful immunity principles present, just as they undoubtedly come directly into operation in the course of the therapeutic action of the antiserum. Neufeld first proposed to use the opsonins as an index of activity of the antiserum, and a convenient method of standardization based upon the opsonins has been given by J Obling. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.<

ISBN: 9781331181828

Paperback, [PU: Forgotten Books], Excerpt from International Clinics, Vol. 4: A Quarterly of Illustrated Clinical Lectures and Especially Prepared Original Articles on Treatment, Medicine… Plus…

Paperback, [PU: Forgotten Books], Excerpt from International Clinics, Vol. 4: A Quarterly of Illustrated Clinical Lectures and Especially Prepared Original Articles on Treatment, Medicine, Surgery, Neurology, Pædiatrics, Obstetrics, Gynæcology, Orthopædics, Pathology, Dermatology, Ophthalmology, Otology, Rhinology, Laryngology, Hyg The antimeningitis serum, being of the general nature of an anti-endotoxic serum, is not subject to standardization according to the methods employed with the antitoxic sera. The antimeningitis serum possesses, it is true, a certain but definite neutralizing power for the autolysate, but this property cannot be used for pur poses of titration. The anti-endotoxic strength of the serum is probably not a correct measure of its therapeutic value since it is not a measure of other immunity principles contained within the serum, whose action is very important. Moreover, the autolysate does not act in a uniform manner upon young guinea-pigs and mice, which are, on the whole, the laboratory animals most susceptible to its toxic effects. Whether introduced beneath the Skin, into the peri toneal cavity, or, as tested by J Obling, by intracardiac injection, the fatal dose fluctuates greatly in guinea-pigs of 200 grammes weight. The employment of living cultures of the meningococcus for purposes of standardization of the serum is also excluded, by reason of their highly variable pathogenicity, for mice, guinea-pigs and other animals. Nor do we possess at present any means by which the pathogenic properties of the living cultures can be main tained at a fixed and suiciently high level. Moreover, no fixed relation exists between the complement-binding power of the anti serum and its therapeutic activity, and hence this method of titra tion, introduced by Kolle and Wassermann, has had to be aban doned. On the other hand, it now seems not improbable that in the opsonins or bacteriotropins we possesses a measure of the thera peutie activity of the antimeningitis serum. It is not to be supposed that the activity of the antiserum resides Wholly in the opsonins, but it is probable that they are a measure of other useful immunity principles present, just as they undoubtedly come directly into operation in the course of the therapeutic action of the antiserum. Neufeld first proposed to use the opsonins as an index of activity of the antiserum, and a convenient method of standardization based upon the opsonins has been given by J Obling. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works., Surgery<

2015, ISBN: 9781331181828

Erscheinungsdatum: 11.07.2015, Medium: Taschenbuch, Einband: Kartoniert / Broschiert, Titel: International Clinics, Vol. 4, Titelzusatz: A Quarterly of Illustrated Clinical Lectures and E… Plus…

Erscheinungsdatum: 11.07.2015, Medium: Taschenbuch, Einband: Kartoniert / Broschiert, Titel: International Clinics, Vol. 4, Titelzusatz: A Quarterly of Illustrated Clinical Lectures and Especially Prepared Original Articles on Treatment, Medicine, Surgery, Neurology, Pædiatrics, Obstetrics, Gynæcology, Orthopædics, Pathology, Dermatology, Ophthalmology, Ot, Autor: Longcope, W. T., Verlag: Forgotten Books, Sprache: Englisch, Schlagworte: MEDICAL // General, Rubrik: Medizin // Allgemeines, Lexika, Seiten: 370, Informationen: 23:B&W 6 x 9 in or 229 x 152 mm Perfect Bound on White w/Gloss Lam, Gewicht: 496 gr, Verkäufer: averdo Belletristik<

ISBN: 9781331181828

A Quarterly of Illustrated Clinical Lectures and Especially Prepared Original Articles on Treatment, Medicine, Surgery, Neurology, Pædiatrics, Obstetrics, Gynæcology, Orthopædics, Patholo… Plus…

A Quarterly of Illustrated Clinical Lectures and Especially Prepared Original Articles on Treatment, Medicine, Surgery, Neurology, Pædiatrics, Obstetrics, Gynæcology, Orthopædics, Pathology, Dermatology, Ophthalmology, Ot A Quarterly of Illustrated Clinical Lectures and Especially Prepared Original Articles on Treatment, Medicine, Surgery, Neurology, Pædiatrics, Obstetrics, Gynæcology, Orthopædics, Pathology, Dermatology, Ophthalmology, Ot Buch (fremdspr.) Bücher>Fremdsprachige Bücher>Englische Bücher, Forgotten Books<

2015, ISBN: 1331181828

Kartoniert / Broschiert MEDICAL / General, mit Schutzumschlag neu, [PU:Forgotten Books]