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Tumor Suppressor Genes
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Tumor Suppressor Genes - nouveau livre

ISBN: 9780896039865

ID: 6454440

It has become clear that tumors arise from excessive cell proliferation and a c- responding reduction in cell death. Tumors result from the successive accumulation of mutations in key regulatory target genes over time. During the 1980s, a number of oncogenes were characterized, whereas from the 1990s to the present, the emphasis shifted to tumor suppressor genes (TSGs). It has become clear that It has become clear that tumors arise from excessive cell proliferation and a c- responding reduction in cell death. Tumors result from the successive accumulation of mutations in key regulatory target genes over time. During the 1980s, a number of oncogenes were characterized, whereas from the 1990s to the present, the emphasis shifted to tumor suppressor genes (TSGs). It has become clear that oncogenes and tumor suppressor genes function in the same pathways, providing positive and ne- tive growth regulatory activities. The signaling pathways controlled by these genes involve virtually every process in cell biology, including nuclear events, cell cycle, cell death, cytoskeletal, cell membrane, angiogenesis, and cell adhesion effects. Tumor suppressor genes are mutated in hereditary cancer syndromes, as well as somatically in nonhereditary cancers. In their normal state, TSGs control cancer development and p- gression, as well as contribute to the sensitivity of cancers to a variety of therapeutics. Understanding the classes of TSGs, the biochemical pathways they function in, and how they are regulated provides an essential lesson in cancer biology. We cannot hope to advance our current knowledge and to develop new and more effective therapies without understanding the relevant pathways and how they influence the present approaches to therapy. Moreover, it is important to be able to access the powerful tools now available to discover these genes, as well as their links to cell biology and growth control. Books, Children's Books~~Education~~Educational: Sciences, General Science, Tumor Suppressor Genes~~Book~~9780896039865, , , , , , , , , ,, [PU: Humana Press]

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Tumor Suppressor Genes: Volume 1: Pathways and Isolation Strategies - Wafik S. El-Deiry (Editor)
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Wafik S. El-Deiry (Editor):
Tumor Suppressor Genes: Volume 1: Pathways and Isolation Strategies - nouveau livre

ISBN: 9780896039865

Wafik S. El-Deiry (Editor),Hardcover - 2003, Edition: 1,Series: Methods in Molecular Biology Series 222, English-language edition,Pub by Springer-Verlag New York, LLC Textbooks New Books ~~ Medicine~~ Nursing ~~ Oncology & Cancer Tumor-Suppressor-Genes-Volume-1~~Wafik-S-El-Deiry Springer-Verlag New York, LLC A second volume of this two-volume set, Tumor Suppressor Genes, Volume 2: Regulation, Function, and Medical Applications, shows how to explore the cell biology and biochemical function of such encoded proteins, to study its physiological role in vivo, and to use information on TSGs to develop diagnostic and therapeutic strategies for cancer.

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Tumor Suppressor Genes: Volume 1: Pathways and Isolation Strategies - Wafik S. El-Deiry
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Wafik S. El-Deiry:
Tumor Suppressor Genes: Volume 1: Pathways and Isolation Strategies - edition reliée, livre de poche

ISBN: 9780896039865

ID: 9780896039865

Tumor Suppressor Genes: Volume 1: Pathways and Isolation Strategies Tumor-Suppressor-Genes-Volume-1~~Wafik-S-El-Deiry Medicine>Medical Ref>Spec Procedure Hardcover, Springer-Verlag New York, LLC

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Tumor Suppressor Genes - Wafik S. El-Deiry
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Wafik S. El-Deiry:
Tumor Suppressor Genes - nouveau livre

ISBN: 9780896039865

ID: 9780896039865

Medicine & Public Health; Oncology Colon, angiogenesis, cell biology, gene expression, influence, proteins, regulation Books, Springer Nature

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Tumor Suppressor Genes - Wafik S. El-Deiry
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Wafik S. El-Deiry:
Tumor Suppressor Genes - edition reliée, livre de poche

2003, ISBN: 9780896039865

ID: 4405485

[ED: 2], 2nd Revised edition, Hardcover, Buch, [PU: Humana Press Inc.]

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Détails sur le livre
Tumor Suppressor Genes: Volume 1: Pathways and Isolation Strategies

A second volume of this two-volume set, Tumor Suppressor Genes, Volume 2: Regulation, Function, and Medical Applications, shows how to explore the cell biology and biochemical function of such encoded proteins, to study its physiological role in vivo, and to use information on TSGs to develop diagnostic and therapeutic strategies for cancer.

Informations détaillées sur le livre - Tumor Suppressor Genes: Volume 1: Pathways and Isolation Strategies


EAN (ISBN-13): 9780896039865
ISBN (ISBN-10): 0896039862
Version reliée
Date de parution: 2003
Editeur: SPRINGER VERLAG GMBH
520 Pages
Poids: 1,125 kg
Langue: eng/Englisch

Livre dans la base de données depuis 06.03.2007 01:06:38
Livre trouvé récemment le 17.11.2017 22:58:19
ISBN/EAN: 9780896039865

ISBN - Autres types d'écriture:
0-89603-986-2, 978-0-89603-986-5


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