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The Unfolded Protein Response and Cellular Stress, Part C - P. Michael Conn
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P. Michael Conn:
The Unfolded Protein Response and Cellular Stress, Part C - nouveau livre

2011, ISBN: 9780123859280

ID: 226590086

The observation that the living cell contains a mechanism to sense and correct the accumulation of unfolded (or incorrectly folded) proteins in the endoplasmic reticulum was formidable in organizing thoughts about cellular integration. This mechanism both halts further protein synthesis and promotes the production of chaperone proteins that act to relieve this problem. If this problem cannot be corrected, the mechanism can initiate programmed cell death. Aspects of this unfolded protein response (UPR) are conserved from yeast to man, an observation that suggests a key role in the process of maintaining a living cell. The UPR presents a way of understanding cellular regulation, a mechanism for disease and a therapeutic opportunity. This third of three parts provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights. Authors were selected based on research contributions in the area about which they have written and based on their ability to describe their methodological contribution in a clear and reproducible way. They have been encouraged to make use of graphics, comparisons to other methods, and to provide tricks and approaches not revealed in prior publications that make it possible to adapt methods to other systems. The Unfolded Protein Response and Cellular Stress, Part C Bücher > Fremdsprachige Bücher > Englische Bücher gebundene Ausgabe 01.04.2011, Elsevier LTD, Oxford, .201

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Methods in enzymology - Conn, P. Michael
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Conn, P. Michael:
Methods in enzymology - nouveau livre

ISBN: 9780123859280

ID: 739195

This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights. This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights. Science Science eBook, Elsevier Science

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The Unfolded Protein Response and Cellular Stress, Part C - Conn, P. Michael
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Conn, P. Michael:
The Unfolded Protein Response and Cellular Stress, Part C - nouveau livre

2011, ISBN: 012385928X

ID: A12665617

Broschiert MEDICAL / General, SCIENCE / Life Sciences / Molecular Biology, mit Schutzumschlag neu, [PU:Elsevier LTD, Oxford]

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REDIVIVUS Buchhandlung Hanausch Reinhard, 93053 Regensburg
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The Unfolded Protein Response and Cellular Stress, Part C
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The Unfolded Protein Response and Cellular Stress, Part C - Première édition

2011, ISBN: 9780123859280

Edition reliée, ID: 17171178

[ED: 491], 491st edition, Hardcover, Buch, [PU: Academic Press Inc]

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The Unfolded Protein Response and Cellular Stress - Saurabh Jha; Dr. P. Michael Conn
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Saurabh Jha; Dr. P. Michael Conn:
The Unfolded Protein Response and Cellular Stress - edition reliée, livre de poche

2011, ISBN: 9780123859280

ID: 17171178

Hardcover, Buch, [PU: Academic Press Inc]

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Détails sur le livre
The Unfolded Protein Response and Cellular Stress, Part C

The observation that the living cell contains a mechanism to sense and correct the accumulation of unfolded (or incorrectly folded) proteins in the endoplasmic reticulum was formidable in organizing thoughts about cellular integration. This mechanism both halts further protein synthesis and promotes the production of chaperone proteins that act to relieve this problem. If this problem cannot be corrected, the mechanism can initiate programmed cell death. Aspects of this unfolded protein response (UPR) are conserved from yeast to man, an observation that suggests a key role in the process of maintaining a living cell. The UPR presents a way of understanding cellular regulation, a mechanism for disease and a therapeutic opportunity. This third of three parts provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights. Authors were selected based on research contributions in the area about which they have written and based on their ability to describe their methodological contribution in a clear and reproducible way. They have been encouraged to make use of graphics, comparisons to other methods, and to provide tricks and approaches not revealed in prior publications that make it possible to adapt methods to other systems.

Informations détaillées sur le livre - The Unfolded Protein Response and Cellular Stress, Part C


EAN (ISBN-13): 9780123859280
ISBN (ISBN-10): 012385928X
Version reliée
Date de parution: 2011
Editeur: Elsevier LTD, Oxford
407 Pages
Poids: 0,896 kg
Langue: eng/Englisch

Livre dans la base de données depuis 06.03.2007 07:31:33
Livre trouvé récemment le 11.11.2017 19:52:17
ISBN/EAN: 9780123859280

ISBN - Autres types d'écriture:
0-12-385928-X, 978-0-12-385928-0


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