- 5 Résultats
prix le plus bas: € 58,41, prix le plus élevé: € 104,03, prix moyen: € 70,66
1
Design, Synthesis and Evaluation of Novel Inhibitors of CT and DosR : Development of Bisubstrate Analog Inhibitors of Cholera Toxin and -Helix Mimetics as Modulators of Dormancy Survival Regulator - Guangtao Zhang
Commander
sur AbeBooks.fr
€ 58,41
Envoi: € 10,991
CommanderLien sponsorisé
Guangtao Zhang:

Design, Synthesis and Evaluation of Novel Inhibitors of CT and DosR : Development of Bisubstrate Analog Inhibitors of Cholera Toxin and -Helix Mimetics as Modulators of Dormancy Survival Regulator - Livres de poche

2011, ISBN: 3639309693

[EAN: 9783639309690], Nouveau livre, [SC: 10.99], [PU: VDM Verlag Dr. Müller], nach der Bestellung gedruckt Neuware - Printed after ordering - Infectious diseases cause millions of deaths… Plus…

NEW BOOK. Frais d'envoi EUR 10.99 AHA-BUCH GmbH, Einbeck, Germany [51283250] [Note: 5 (sur 5)]
2
Design Synthesis and Evaluation of Novel Inhibitors of CT and DosR - Guangtao Zhang
Commander
sur Hugendubel.de
€ 58,99
Envoi: € 0,001
CommanderLien sponsorisé

Guangtao Zhang:

Design Synthesis and Evaluation of Novel Inhibitors of CT and DosR - Livres de poche

ISBN: 9783639309690

*Design Synthesis and Evaluation of Novel Inhibitors of CT and DosR* - Development of Bisubstrate Analog Inhibitors of Cholera Toxin and -Helix Mimetics as Modulators of Dormancy Survival… Plus…

Frais d'envoiShipping in 1-2 weeks, , Versandkostenfrei nach Hause oder Express-Lieferung in Ihre Buchhandlung., DE. (EUR 0.00)
3
Design Synthesis and Evaluation of Novel Inhibitors of CT and DosR - Guangtao Zhang
Commander
sur Hugendubel.de
€ 58,99
Envoi: € 0,001
CommanderLien sponsorisé
Guangtao Zhang:
Design Synthesis and Evaluation of Novel Inhibitors of CT and DosR - Livres de poche

ISBN: 3639309693

Design Synthesis and Evaluation of Novel Inhibitors of CT and DosR ab 58.99 € als Taschenbuch: Development of Bisubstrate Analog Inhibitors of Cholera Toxin and -Helix Mimetics as Modulat… Plus…

Nr. 14550045. Frais d'envoi, , DE. (EUR 0.00)
4
Commander
sur Biblio.co.uk
$ 113,23
(environ € 104,03)
Envoi: € 14,031
CommanderLien sponsorisé
Zhang, Guangtao:
Design, Synthesis and Evaluation of Novel Inhibitors of CT and DosR: Development of Bisubstrate Analog Inhibitors of Cholera Toxin and ?-Helix Mimetics as Modulators of Dormancy Survival Regulator - Livres de poche

ISBN: 9783639309690

paperback. Good. Access codes and supplements are not guaranteed with used items. May be an ex-library book., 2.5

Frais d'envoi EUR 14.03 Bonita
5
Commander
sur alibris.co.uk
€ 72,86
CommanderLien sponsorisé
Zhang, Guangtao:
Design, Synthesis and Evaluation of Novel Inhibitors of CT and DosR - Livres de poche

2011, ISBN: 9783639309690

Trade paperback, New., Trade paperback (US). Glued binding. 160 p., [PU: VDM Verlag]

Frais d'envoiLivraison non-comprise Uxbridge, MIDDLESEX, Ria Christie Books

1Comme certaines plateformes ne transmettent pas les conditions d'expédition et que celles-ci peuvent dépendre du pays de livraison, du prix d'achat, du poids et de la taille de l'article, d'une éventuelle adhésion de la plateforme, d'une livraison directe par la plateforme ou via un prestataire tiers (Marketplace), etc. il est possible que les frais de livraison indiqués par eurolivre ne correspondent pas à ceux de la plateforme qui propose l'article.

Données bibliographiques du meilleur livre correspondant

Détails sur le livre
Design Synthesis and Evaluation of Novel Inhibitors of CT and DosR

Infectious diseases cause millions of deaths each year. The top single disease killers include tuberculosis and diarrheal diseases. The diarrheal diseases caused by cholera toxin and E. coli heat-labile enterotoxin constitute a large part of the diarrhea-related deaths worldwide each year. While there are some efficacious drugs against Vibrio cholerae in the market, their resistance is developing quickly. We wish to develop synthetic molecules that could bind to CT with a high affinity to block the enzymatic reaction catalyzed by CT. We designed, synthesized and evaluated bisubstrate analogs targeting the active site of CT. The most potent inhibitor demonstrated an IC50 of around 40 µM. It could serve as a promising drug to treat cholera. The second project is to use a-helix mimetics for probing the protein-protein interactions of DosR. The main function of DosR is to mediate the transition of Mycobacteria tuberculosis into dormancy and may contribute to latency. Disruption of the dimerization of DosR could keep MTB in an active state, so that the existing drugs could treat them effectively. We employed small molecules and peptides as tools to achieve the goal.

Informations détaillées sur le livre - Design Synthesis and Evaluation of Novel Inhibitors of CT and DosR


EAN (ISBN-13): 9783639309690
ISBN (ISBN-10): 3639309693
Version reliée
Livre de poche
Date de parution: 2011
Editeur: VDM Verlag Dr. Müller

Livre dans la base de données depuis 2009-07-01T15:06:36+02:00 (Paris)
Page de détail modifiée en dernier sur 2023-06-25T11:07:36+02:00 (Paris)
ISBN/EAN: 3639309693

ISBN - Autres types d'écriture:
3-639-30969-3, 978-3-639-30969-0
Autres types d'écriture et termes associés:
Auteur du livre: zhang
Titre du livre: synthesis, helix


< pour archiver...