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Drug Metabolism and Transport: Molecular Methods and Mechanisms - Herausgegeben von Lash, Lawrence H.
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Herausgegeben von Lash, Lawrence H.:

Drug Metabolism and Transport: Molecular Methods and Mechanisms - Livres de poche

2010, ISBN: 9781617374944

[ED: Softcover], [PU: Springer, Berlin], A compendium of proven experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, S-transferase, glucuronidation, N-acetylation, and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low molecular-weight cofactors can alter drug metabolism, and how modulation of drug metabolism pathways can influence antiviral therapy. Remarkable advances in molecular and cell biology and the development of novel in vitro model systems have greatly expanded our knowledge of the processes involved in metabolism and transport and led to numerous new therapeutic approaches. In Drug Metabolism and Transport: Molecular Methods and Mechanisms, well-established investigators describe their best experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, glucuronidation, N-acetylation, and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low-molecular-weight cofactors can alter drug metabolism, and how modulation of drug metabolism pathways can influence antiviral therapy. The strategies detailed for transport phenomena cover the multidrug resistance proteins, the reduced folate carrier, the plasma membrane, and mitochondrial glutathione transporters, and can be applied to numerous other transport systems. Many chapters contain step-by-step methods for investigating metabolism and transport.Insightful and broad-ranging, Drug Metabolism and Transport: Molecular Methods and Mechanisms offers novice and experienced investigators alike a highly useful compendium of key strategies and approaches to successful research on drug metabolism and transport pathways.2010. x, 388 S. 110 SW-Abb. 229 mmVersandfertig in über 4 Wochen, [SC: 0.00], Neuware, gewerbliches Angebot

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Drug Metabolism and Transport: Molecular Methods and Mechanisms - Springer
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Drug Metabolism and Transport: Molecular Methods and Mechanisms - nouveau livre

2010, ISBN: 9781617374944

ID: 660789187

A compendium of proven experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, S-transferase, glucuronidation, N-acetylation, and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low molecular-weight cofactors can alter drug metabolism, and how modulation of drug metabolism pathways can influence antiviral therapy. Remarkable advances in molecular and cell biology and the development of novel in vitro model systems have greatly expanded our knowledge of the processes involved in metabolism and transport and led to numerous new therapeutic approaches. In Drug Metabolism and Transport: Molecular Methods and Mechanisms, well-established investigators describe their best experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, glucuronidation, N-acetylation, and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low-molecular-weight cofactors can alter drug metabolism, and how modulation of drug metabolism pathways can influence antiviral therapy. The strategies detailed for transport phenomena cover the multidrug resistance proteins, the reduced folate carrier, the plasma membrane, and mitochondrial glutathione transporters, and can be applied to numerous other transport systems. Many chapters contain step-by-step methods for investigating metabolism and transport. Insightful and broad-ranging, Drug Metabolism and Transport: Molecular Methods and Mechanisms offers novice and experienced investigators alike a highly useful compendium of key strategies and approaches to successful research on drug metabolism and transport pathways. Molecular Methods and Mechanisms Bücher > Fremdsprachige Bücher > Englische Bücher Taschenbuch 09.11.2010, Springer, .201

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Drug Metabolism and Transport: Molecular Methods and Mechanisms (Methods in Pharmacology and Toxicology) - Lawrence H. Lash (Editor)
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Lawrence H. Lash (Editor):
Drug Metabolism and Transport: Molecular Methods and Mechanisms (Methods in Pharmacology and Toxicology) - Livres de poche

ISBN: 9781617374944

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Drug Metabolism and Transport: Molecular Methods and Mechanisms - Lawrence H. Lash
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Lawrence H. Lash:
Drug Metabolism and Transport: Molecular Methods and Mechanisms - Livres de poche

ISBN: 9781617374944

ID: 9781617374944

Drug Metabolism and Transport: Molecular Methods and Mechanisms Drug-Metabolism-and-Transport~~Lawrence-H-Lash Medicine>Health Professions>Pharmacology Paperback, Springer-Verlag New York, LLC

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Drug Metabolism and Transport - Lawrence H. Lash
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Lawrence H. Lash:
Drug Metabolism and Transport - Livres de poche

2010, ISBN: 9781617374944

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1st ed. Softcover of orig. ed. 2005, Softcover, Buch, [PU: Humana Press Inc.]

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Détails sur le livre
Drug Metabolism and Transport: Molecular Methods and Mechanisms
Auteur:

Herausgegeben von Lash, Lawrence H.

Titre:

Drug Metabolism and Transport: Molecular Methods and Mechanisms

ISBN:

1617374946

A compendium of proven experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, S-transferase, glucuronidation, N-acetylation, and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low molecular-weight cofactors can alter drug metabolism, and how modulation of drug metabolism pathways can influence antiviral therapy.

Informations détaillées sur le livre - Drug Metabolism and Transport: Molecular Methods and Mechanisms


EAN (ISBN-13): 9781617374944
ISBN (ISBN-10): 1617374946
Version reliée
Livre de poche
Date de parution: 2010
Editeur: SPRINGER VERLAG GMBH
400 Pages
Poids: 0,585 kg
Langue: eng/Englisch

Livre dans la base de données depuis 21.10.2011 19:46:36
Livre trouvé récemment le 17.11.2016 20:44:25
ISBN/EAN: 1617374946

ISBN - Autres types d'écriture:
1-61737-494-6, 978-1-61737-494-4

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