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Vaccinia Virus and Poxvirology: Methods and Protocols - Stuart N. Isaacs (Editor)
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ISBN: 9781617374371

Recombinant vaccinia viruses have become important in recent years, both as protein expression vectors, and-in the age of bioterrorism-as powerful tools for developing new smallpox vaccines, diagnostics, and understanding of poxvirus pathogenesis. In Vaccinia Virus and Poxvirology: Methods and Prools, internationally recognized experts and leaders in poxvirology describe in step-by-step detail the successful techniques they have perfected to study and work with vaccinia virus and other poxviruses. They offer cutting-edge techniques for the construction and characterization of recombinant viruses; for the study of poxvirus gene transcription and DNA replication; and for the use of the virus in immunologic and cell-cell fusion assays. Other methods cover poxvirus bioinformatics, aspects of viral pathogenesis at both a protein and an animal model level, and the study of immune responses to poxvirus-the latter critical to the important role of vaccinia virus in smallpox vaccination and its potential role as a vaccine vector directed against infectious agents and cancer. The prools presented follow the successful Methods in Molecular Biology™ series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and timely, Vaccinia Virus and Poxvirology: Methods and Prools offers virologists and vaccinologists an unequaled source of proven techniques for understanding poxviruses and developing defenses against their use as bioterrorist agents. Textbooks New Books ~~ Science~~ Life Sciences ~~ Microbiology Vaccinia-Virus-and-Poxvirology~~Stuart-N-Isaacs Springer-Verlag New York, LLC A comprehensive collection of cutting-edge methods to study and work with the vaccinia virus and other poxvirus gene transcriptions. These readily reproducible techniques can be used for the construction and characterization of recombinant viruses; for the study of poxvirus gene transcription and DNA replication; for the investigation of the binding, entry, and movement of the virus in host cells; and for the use of the virus in immunologic and cell-cell fusion assays. Other methods cover poxvirus bioinformatics, aspects of viral pathogenesis at both a protein and an animal model level, and the study of immune responses to poxviruses-the latter a critical ability given the important role of vaccinia virus in smallpox vaccination and their potential role as vaccine vectors directed against infectious agents and cancer.

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Vaccinia Virus and Poxvirology: Methods and Protocols (Methods in Molecular Biology) - Stuart N. Isaacs
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Stuart N. Isaacs:
Vaccinia Virus and Poxvirology: Methods and Protocols (Methods in Molecular Biology) - Livres de poche

ISBN: 1617374377

[SR: 5875959], Paperback, [EAN: 9781617374371], Humana Press, Humana Press, Book, [PU: Humana Press], Humana Press, The Right Book at the Right Time The poxviruses comprise a family of complex DNA viruses that replicate in the cytoplasm of vertebrate or invertebrate cells. Of the eight recognized g- era of vertebrate poxviruses, those belonging to the orthopoxvirus genus have been most intensively studied. This group includes variola virus, the agent of smallpox, as well as cowpox virus and vaccinia virus. Jenner’s original sma- pox vaccine, described in 1798, consisted of live cowpox virus, but vaccinia virus later replaced it (1). There has been speculation as to the origin of v- cinia virus; the most likely idea is that it is a separate species, possibly ori- nally isolated from a horse, and is now extinct or rare in nature (2). Recent genome sequencing studies confirm the distinctness of variola virus, cowpox virus, and vaccinia virus and also their very close genetic relationship, which accounts for the cross protection of smallpox vaccines. The novelty of the smallpox vaccine can be readily appreciated by the time it took, about 80 years, before the next live vaccine against rabies was developed, and another 50 years for the yellow fever vaccine. Moreover, the eradication of smallpox in 1977 stands as a unique medical achievement. Because of its historical role, sma- pox vaccination contributed greatly to present concepts of infectious disease, immunity, and pathogenesis. Less well known, however, are the many other “firsts” for vac, 172406, Microbiology, 226688, Biology, 13469, Biological Sciences, 75, Science & Math, 1000, Subjects, 283155, Books, 227192, Immunology, 227191, Basic Sciences, 173514, Medical Books, 1000, Subjects, 283155, Books, 689715011, Immunology, 689709011, Basic Sciences, 689674011, Medicine, 468228, Medicine & Health Sciences, 465600, New, Used & Rental Textbooks, 2349030011, Specialty Boutique, 283155, Books, 689716011, Microbiology, 689709011, Basic Sciences, 689674011, Medicine, 468228, Medicine & Health Sciences, 465600, New, Used & Rental Textbooks, 2349030011, Specialty Boutique, 283155, Books, 684289011, Biology, 491702, Biology & Life Sciences, 468216, Science & Mathematics, 465600, New, Used & Rental Textbooks, 2349030011, Specialty Boutique, 283155, Books

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Vaccinia Virus and Poxvirology: Methods and Protocols (Methods in Molecular Biology) - Stuart N. Isaacs
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Stuart N. Isaacs:
Vaccinia Virus and Poxvirology: Methods and Protocols (Methods in Molecular Biology) - Livres de poche

ISBN: 1617374377

[SR: 5875959], Paperback, [EAN: 9781617374371], Humana Press, Humana Press, Book, [PU: Humana Press], Humana Press, The Right Book at the Right Time The poxviruses comprise a family of complex DNA viruses that replicate in the cytoplasm of vertebrate or invertebrate cells. Of the eight recognized g- era of vertebrate poxviruses, those belonging to the orthopoxvirus genus have been most intensively studied. This group includes variola virus, the agent of smallpox, as well as cowpox virus and vaccinia virus. Jenner’s original sma- pox vaccine, described in 1798, consisted of live cowpox virus, but vaccinia virus later replaced it (1). There has been speculation as to the origin of v- cinia virus; the most likely idea is that it is a separate species, possibly ori- nally isolated from a horse, and is now extinct or rare in nature (2). Recent genome sequencing studies confirm the distinctness of variola virus, cowpox virus, and vaccinia virus and also their very close genetic relationship, which accounts for the cross protection of smallpox vaccines. The novelty of the smallpox vaccine can be readily appreciated by the time it took, about 80 years, before the next live vaccine against rabies was developed, and another 50 years for the yellow fever vaccine. Moreover, the eradication of smallpox in 1977 stands as a unique medical achievement. Because of its historical role, sma- pox vaccination contributed greatly to present concepts of infectious disease, immunity, and pathogenesis. Less well known, however, are the many other “firsts” for vac, 172406, Microbiology, 226688, Biology, 13469, Biological Sciences, 75, Science & Math, 1000, Subjects, 283155, Books, 227192, Immunology, 227191, Basic Sciences, 173514, Medical Books, 1000, Subjects, 283155, Books, 689715011, Immunology, 689709011, Basic Sciences, 689674011, Medicine, 468228, Medicine & Health Sciences, 465600, New, Used & Rental Textbooks, 2349030011, Specialty Boutique, 283155, Books, 689716011, Microbiology, 689709011, Basic Sciences, 689674011, Medicine, 468228, Medicine & Health Sciences, 465600, New, Used & Rental Textbooks, 2349030011, Specialty Boutique, 283155, Books, 684289011, Biology, 491702, Biology & Life Sciences, 468216, Science & Mathematics, 465600, New, Used & Rental Textbooks, 2349030011, Specialty Boutique, 283155, Books

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Vaccinia Virus and Poxvirology: Methods and Protocols (Paperback)
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Vaccinia Virus and Poxvirology: Methods and Protocols (Paperback) - Livres de poche

2010, ISBN: 1617374377

ID: 13955276961

[EAN: 9781617374371], Neubuch, [PU: Humana Press Inc., United States], Language: English Brand New Book ***** Print on Demand *****. The Right Book at the Right Time The poxviruses comprise a family of complex DNA viruses that replicate in the cytoplasm of vertebrate or invertebrate cells. Of the eight recognized g- era of vertebrate poxviruses, those belonging to the orthopoxvirus genus have been most intensively studied. This group includes variola virus, the agent of smallpox, as well as cowpox virus and vaccinia virus. Jenner s original sma- pox vaccine, described in 1798, consisted of live cowpox virus, but vaccinia virus later replaced it (1). There has been speculation as to the origin of v- cinia virus; the most likely idea is that it is a separate species, possibly ori- nally isolated from a horse, and is now extinct or rare in nature (2). Recent genome sequencing studies confirm the distinctness of variola virus, cowpox virus, and vaccinia virus and also their very close genetic relationship, which accounts for the cross protection of smallpox vaccines. The novelty of the smallpox vaccine can be readily appreciated by the time it took, about 80 years, before the next live vaccine against rabies was developed, and another 50 years for the yellow fever vaccine. Moreover, the eradication of smallpox in 1977 stands as a unique medical achievement. Because of its historical role, sma- pox vaccination contributed greatly to present concepts of infectious disease, immunity, and pathogenesis. Less well known, however, are the many other firsts for vaccinia virus.

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Vaccinia Virus and Poxvirology - Stuart N. Isaacs
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Vaccinia Virus and Poxvirology - Livres de poche

2010, ISBN: 9781617374371

ID: 16168405

1st ed. Softcover of orig. ed. 2004, Softcover, Buch, [PU: Humana Press Inc.]

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Détails sur le livre
Vaccinia Virus and Poxvirology: Methods and Protocols

A comprehensive collection of cutting-edge methods to study and work with the vaccinia virus and other poxvirus gene transcriptions. These readily reproducible techniques can be used for the construction and characterization of recombinant viruses; for the study of poxvirus gene transcription and DNA replication; for the investigation of the binding, entry, and movement of the virus in host cells; and for the use of the virus in immunologic and cell-cell fusion assays. Other methods cover poxvirus bioinformatics, aspects of viral pathogenesis at both a protein and an animal model level, and the study of immune responses to poxviruses-the latter a critical ability given the important role of vaccinia virus in smallpox vaccination and their potential role as vaccine vectors directed against infectious agents and cancer.

Informations détaillées sur le livre - Vaccinia Virus and Poxvirology: Methods and Protocols


EAN (ISBN-13): 9781617374371
ISBN (ISBN-10): 1617374377
Livre de poche
Date de parution: 2010
Editeur: SPRINGER VERLAG GMBH
416 Pages
Langue: eng/Englisch

Livre dans la base de données depuis 02.11.2011 20:49:46
Livre trouvé récemment le 13.08.2017 01:18:24
ISBN/EAN: 1617374377

ISBN - Autres types d'écriture:
1-61737-437-7, 978-1-61737-437-1


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