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Molecular Pathology of Hematolymphoid Diseases - edition reliée, livre de poche

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Molecular Pathology of Hematolymphoid Diseases

The past two decades have seen an ever-accelerating growth in knowledge about molecular pathology of human diseases which received a large boost with the sequencing of the human genome in 2003. Molecular diagnostics, molecular targeted therapy and genetic therapy are now routine in many medical centers. The molecular field now impacts every field in medicine, whether clinical research or routine patient care. There is a great need for basic researchers to understand the potential clinical implications of their research whereas private practice clinicians of all types (general internal medicine and internal medicine specialists, medical oncologists, radiation oncologists, surgeons, pediatricians, family practitioners), clinical investigators, pathologists and medical laboratory directors and radiologists require a basic understanding of the fundamentals of molecular pathogenesis, diagnosis and treatment for their patients. Traditional textbooks in molecular biology deal with basic science and are not readily applicable to the medical setting. Most medical textbooks that include a mention of molecular pathology in the clinical setting are limited in scope and assume that the reader already has a working knowledge of the basic science of molecular biology. Other texts emphasize technology and testing procedures without integrating the clinical perspective. There is an urgent need for a text that fills the gap between basic science books and clinical practice. In the Molecular Pathology Library series the basic science and the technology is integrated with the medical perspective and clinical application. Each book in the series is divided according to neoplastic and non-neoplastic diseases for each of the organ systems traditionally associated with medical subspecialties. Each book in the series is organized to provide specific application of molecular pathology to the pathogenesis, diagnosis and treatment of neoplastic and non-neoplastic diseases specific to each organ system. These broad section topics are broken down into succinct chaptersto cover a very specific disease entity. The chapters are written by established authorities on the specific topic from academic centers around the world. In one book, diverse subjects are included that the reader would have to pursue from multiple sources in order to have a clear understanding of the molecular pathogenesis, diagnosis and treatment of specific diseases. Attempting to hunt for the full information from basic concept to specific applications for a disease from varied sources is time-consuming and frustrating. By providing this quick and user-friendly reference, understanding and application of this rapidly growing field is made more accessible to both expert and generalist alike. As books that bridge the gap between basic science and clinical understanding and practice, the Molecular Pathology Series serves the basic scientist, the clinical researcher and the practicing physician or other health care provider who require more understanding of the application of basic research to patient care, from "bench to bedside." This series is unique and an invaluable resource to those who need to know about molecular pathology from a clinical, disease-oriented perspective. These books will be indispensable to physicians and health care providers in multiple disciplines as noted above, to residents and fellows in these multiple disciplines as well as their teaching institutions and to researchers who increasingly must justify the clinical implications of their research.

Informations détaillées sur le livre - Molecular Pathology of Hematolymphoid Diseases


EAN (ISBN-13): 9781441956972
ISBN (ISBN-10): 1441956972
Version reliée
Livre de poche
Date de parution: 2010
Editeur: Springer US
625 Pages
Poids: 1,979 kg
Langue: eng/Englisch

Livre dans la base de données depuis 2009-05-28T14:33:55+02:00 (Paris)
Page de détail modifiée en dernier sur 2023-09-15T11:34:55+02:00 (Paris)
ISBN/EAN: 1441956972

ISBN - Autres types d'écriture:
1-4419-5697-2, 978-1-4419-5697-2
Autres types d'écriture et termes associés:
Auteur du livre: dunphy
Titre du livre: pathology, molecular


Données de l'éditeur

Auteur: Cherie H. Dunphy
Titre: Molecular Pathology Library; Molecular Pathology of Hematolymphoid Diseases
Editeur: Springer; Springer US
620 Pages
Date de parution: 2010-04-27
New York; NY; US
Langue: Anglais
213,99 € (DE)
219,99 € (AT)
236,00 CHF (CH)
Available
XIX, 620 p. 122 illus., 93 illus. in color.

BB; Hardcover, Softcover / Medizin/Klinische Fächer; Pathologie; Verstehen; bone marrow; cancer; chromosome; diagnostics; gene expression; gene therapy; genetics; genome; internal medicine; lymphoma; molecular biology; molecular genetics; molecular pathology; pathogenesis; stem cells; Pathology; EA; BC

Molecular Pathology of Hematolymphoid Neoplasms: General Principles.- Molecular Oncogenesis.- Genetic Predispositions for Hematologic and Lymphoid Disorders.- Prognostic Markers.- Cancer Stem Cells: Potential Targets for Molecular Medicine.- Gene Therapy for Leukemia and Lymphoma.- Chemical and Environmental Agents (Including Chemotherapeutic Agents and Immunosuppression).- Viral Oncogenesis.- Specific Techniques and Their Applications in Molecular Hematopathology.- Techniques to Determine Clonality in Hematolymphoid Malignancies.- Techniques to Detect Defining Chromosomal Translocations/Abnormalities.- Molecular Techniques to Detect Disease and Response to Therapy: Minimal Residual Disease.- Detection of Resistance to Therapy in Hematolymphoid Neoplasms.- Monitoring Engraftment of Bone Marrow Transplant by DNA Fingerprinting.- Gene Expression Profiling.- Proteomics of Human Malignant Lymphoma.- Mouse Models of Hematolymphoid Malignancies.- Molecular Pathology of Hematolymphoid Neoplasms: Specific Subtypes.- Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.- Marginal Zone B-Cell Lymphoma.- Lymphoplasmacytic Lymphoma.- Molecular Pathology of Plasma Cell Neoplasms.- The Roles of Molecular Techniques in the Diagnosis and Management of Follicular Lymphoma.- Mantle Cell Lymphoma.- Diffuse Large B-Cell Lymphomas.- The Molecular Pathology of Burkitt Lymphoma.- Precursor B-Cell Acute Lymphoblastic Leukemia.- Molecular Genetics of Mature T/NK Neoplasms.- Precursor T-Cell Neoplasms.- Classical Hodgkin Lymphoma and Nodular Lymphocyte Predominant Hodgkin Lymphoma.- Posttransplant Lymphoproliferative Disorder.- AIDS-Related Lymphomas.- Chronic Myelogenous Leukemia.- Molecular Pathogenesis of Nonchronic Myeloid Leukemia Myeloproliferative Neoplasms.- Molecular Pathology of Myelodysplastic/Myeloproliferative Neoplasms, Myeloid and Lymphoid Neoplasms with Eosinophilia and Abnormalities of PDGFRA, PDGFRB, and FGFR1, and Mastocytosis.- Molecular Pathogenesis of Myelodysplastic Syndromes.- Acute Myeloid Leukemias with Recurrent Cytogenetic Abnormalities.- Acute Myeloid Leukemias with Normal Cytogenetics.- Acute Myeloid Leukemia with Myelodysplasia-Related Changes and Therapy-Related Acute Myeloid Leukemia.- Molecular Pathology of Hemoglobin and Erythrocyte Membrane Disorders.- White Blood Cell and Immunodeficiency Disorders.- Molecular Basis of Disorders of Hemostasis and Thrombosis.- Sarcoidosis: Are There Sarcoidosis Genes?.- Castleman’s Disease.- Molecular Pathology of Histiocytic Disorders.- Reactive Lymphadenopathies: Molecular Analysis.- Molecular Pathology of Infectious Lymphadenitides.- Gene Therapy for Nonneoplastic Hematologic and Histiocytic Disorders.
Integrated with a medical perspective Divided according to neoplastic and non-neoplastic disease Each chapter focuses on a specific disease entity Quick and user-friendly reference Includes supplementary material: sn.pub/extras

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