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Alpha-Gal specific humoral immune response to bioprostheses : Biological heart valve implantation triggers the amplification of specific antibodies - Andreas Mangold
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Alpha-Gal specific humoral immune response to bioprostheses : Biological heart valve implantation triggers the amplification of specific antibodies - Livres de poche

2010, ISBN: 3639288378

[EAN: 9783639288377], Neubuch, [PU: VDM Verlag Dr. Müller], nach der Bestellung gedruckt Neuware - Printed after ordering - It has been shown that alpha-Gal is a relevant xenoantigen pres… Plus…

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Alpha-Gal specific humoral immune response to bioprostheses - Livres de poche

2010, ISBN: 9783639288377

[ED: Softcover], [PU: VDM Verlag Dr. Müller], It has been shown that alpha-Gal is a relevant xenoantigen present on bioprostheses and elicits a specific IgM immune response. The aim of th… Plus…

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Alpha-Gal specific humoral immune response to bioprostheses Andreas Mangold Author - nouveau livre

ISBN: 9783639288377

It has been shown that alpha-Gal is a relevant xenoantigen present on bioprostheses and elicits a specific IgM immune response. The aim of this work was to investigate whether that immune… Plus…

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Mangold, A: Alpha-Gal specific humoral immune response to bi - nouveau livre

ISBN: 9783639288377

It has been shown that alpha-Gal is a relevant xenoantigen present on bioprostheses and elicits a specific IgM immune response. The aim of this work was to investigate whether that immune… Plus…

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Alpha-Gal specific humoral immune response to bioprostheses - Livres de poche

ISBN: 9783639288377

Paperback, [PU: VDM Verlag], It has been shown that alpha-Gal is a relevant xenoantigen present on bioprostheses and elicits a specific IgM immune response. The aim of this work was to in… Plus…

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Alpha-Gal specific humoral immune response to bioprostheses Andreas Mangold Author

It has been shown that alpha-Gal is a relevant xenoantigen present on bioprostheses and elicits a specific IgM immune response. The aim of this work was to investigate whether that immune response proceeds after valve implantation. Plasma samples were collected from patients who underwent biovalve implantation or mechanical valve replacement, prior to, at ten days and at three months after cardiac surgery. ELISA was performed to quantify Gal specific antibodies. Three bioprosthetic tissue samples were obtained from patients who had to undergo reoperation within one week or one year after the initial operation. Presence of Gal epitopes and cell nuclei was determined. Alpha-Gal specific IgG was significantly increased three months after implantation of bioprostheses. In explanted bioprostheses one year after implantation, no Gal epitopes could be detected. These results indicate that the implantation of bioprostheses elicits a specific immune response against Gal bearing cells. The complete absence of Gal positive structures 12 months after implantation indicates a specific degradation of Gal bearing cells through previous exposure to the human blood circuit.

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EAN (ISBN-13): 9783639288377
ISBN (ISBN-10): 3639288378
Version reliée
Livre de poche
Date de parution: 2010
Editeur: VDM Verlag Core >1 >T

Livre dans la base de données depuis 2007-07-14T16:59:59+02:00 (Paris)
Page de détail modifiée en dernier sur 2024-01-17T14:48:51+01:00 (Paris)
ISBN/EAN: 3639288378

ISBN - Autres types d'écriture:
3-639-28837-8, 978-3-639-28837-7
Autres types d'écriture et termes associés:
Auteur du livre: mangold
Titre du livre: alpha plus, gal buch


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