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Alternative pre-mRNA Splicing - Smith, Chris; Stamm, Stefan; L&uuml-hrmann, Reinhard
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Smith, Chris; Stamm, Stefan; L&uuml-hrmann, Reinhard:

Alternative pre-mRNA Splicing - nouveau livre

ISBN: 9783527326068

ID: 837577

Stefan Stamm is Associate Professor in the Department for Molecular and Cellular Biochemistry at the University of Kentucky. He studied Biochemistry in Hannover (Germany) and did the practical work for his PhD as well as postdoctoral work at the Cold Spring Harbor Laboratory, NY. His research focuses on mechanisms and regulation of alternative splicing, with the aim to apply the fi ndings to the Prader-Willi Syndrome and Spinal Muscular Atrophy. Chris Smith is Professor of RNA Molecular Biology in the Department of Biochemistry at the University of Cambridge. His PhD research in Biochemistry was carried out at the University of London, followed by postdoctoral research at Harvard Medical School. His research interests encompass the mechanisms, regulation and function of alternative splicing. Reinhard Lührmann is Director at the Max Planck Institute for Biophysical Chemistry in Göttingen where he is head of the Department of Cellular Biochemistry. He is an Honorary Professor at the University of Göttingen. He has studied chemistry at the University of Münster where he also received his PhD. He worked as a postdoctoral fellow at the Max Planck Institute for Molecular Genetics in Berlin. His research focuses on the structure and mechanism of the spliceosome. Technology Technology eBook, Wiley

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Alternative Pre-Mrna Splicing: Theory and Protocols - Stamm, Stefan / Smith, Chris / L?hrmann, Reinhard
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Stamm, Stefan / Smith, Chris / L?hrmann, Reinhard:

Alternative Pre-Mrna Splicing: Theory and Protocols - livre d'occasion

ISBN: 9783527326068

ID: 13425429

RNA splicing is the process by which the non-coding regions of pre-messenger RNA are removed and mRNA takes its mature form which is subsequently translated to proteins. RNA splicing heavily relies on signalling mechanisms and, depending on the presence and availability of different signalling molecules, alternative splicing at different sites of the mRNA can occur. This leads to a variation in mRNA procucts derived from the same pre mRNA, and cosequently gives rise to protein products which might differ in sequence and function. Major advances in the detection methods of splicing variants during last decade have demonstrated that alternative splicing underlies many diseases such as Cystic Fibrosis, Fragile X syndrome and different types of cancer. This has not only enforced the need to further elucidate splicing mechanisms, but has also highlighted the need to study alternative splicing at a clinical level. The present book provides all the basic background information on splicing and aims to serve as a laboratory manual for all researchers and doctors who use methods to select splicing variants in the lab and in the clinic. Alternative Pre-Mrna Splicing: Theory and Protocols Stamm, Stefan / Smith, Chris / L?hrmann, Reinhard, Wiley-VCH Verlag GmbH

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Alternative pre-mrna splicing: theory and protocols
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Alternative pre-mrna splicing: theory and protocols - nouveau livre

ISBN: 9783527326068

ID: D416d3fb3cbae91ae661a4f0df3f6c6d7

This book was written for graduate and medical students, as well as clinicians and postdoctoral researchers. It describes the theory of alternative pre-mRNA splicing in twelve introductory chapters and then introduces protocols and their theoretical background relevant for experimental research. These 43 practical chapters cover: Basic methods, Detection of splicing events, Analysis of alternative pre-mRNA splicing in vitro and in vivo, Manipulation of splicing events, and Bioinformatic analysis of alternative splicing. A theoretical introduction and practical guide for molecular biologists, geneticists,clinicians and every researcher interested in alternative splicing. Website: www.wiley-vch.de/home/splicing NL true, [PU: Wiley-VCH, Weinheim]

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Alternative pre-mRNA Splicing - Wiley-VCH
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Wiley-VCH:
Alternative pre-mRNA Splicing - nouveau livre

ISBN: 9783527326068

ID: b29bd25e22b5263a1f62cf837c592102

Theory and Protocols Bücher / Fremdsprachige Bücher / Englische Bücher 978-3-527-32606-8, Wiley-VCH

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Alternative pre-mRNA Splicing - Stefan Stamm; Chris Smith; Reinhard Lührmann
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Stefan Stamm; Chris Smith; Reinhard Lührmann:
Alternative pre-mRNA Splicing - Première édition

2012, ISBN: 9783527326068

Livres de poche, ID: 14874508

Theory and Protocols, [ED: 1], 1. Auflage, Softcover, Buch, [PU: Wiley-VCH]

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Détails sur le livre
Alternative pre-mRNA Splicing
Auteur:

Stefan Stamm

Titre:

Alternative pre-mRNA Splicing

ISBN:

9783527326068

Der definitive Leitfaden zum RNA-Splicing -- ideal für alle Kliniker, die sich mit genetischen Erkrankungen befassen, insbesondere natürlich für RNA-Forscher.

Informations détaillées sur le livre - Alternative pre-mRNA Splicing


EAN (ISBN-13): 9783527326068
ISBN (ISBN-10): 3527326065
Version reliée
Livre de poche
Date de parution: 20120111
Editeur: Wiley VCH Verlag GmbH
622 Pages
Poids: 1,997 kg
Langue: Englisch

Livre dans la base de données depuis 20.02.2012 14:54:00
Livre trouvé récemment le 20.12.2016 13:54:56
ISBN/EAN: 9783527326068

ISBN - Autres types d'écriture:
3-527-32606-5, 978-3-527-32606-8

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