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Recombinant Antibodies for Cancer Therapy: Methods and Protocols - Martin Welschof#Jürgen Krauss
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Martin Welschof#Jürgen Krauss:

Recombinant Antibodies for Cancer Therapy: Methods and Protocols - nouveau livre

ISBN: 9780896039186

ID: 170890278

Since the advent of hybridoma technology more than two decades ago, numerous antibodies have entered the clinical setting as potent therapeutic agents. Their repeated application in humans, however, is limited by the development of human antimouse antibodies (HAMA) in the recipient, leading to allergic re- tions against the foreign murine protein and rapid neutralization. To circumvent these limitations many new antibodies have recently been tailored through recombinant antibody technology. The initial clinical data show encouraging results, thus demonstrating the potential of these new therapeutic agents. The purpose of Recombinant Antibodies for Cancer Therapy is to present a collection of detailed protocols in recombinant antibody technology. It is pri- rily addressed to scientists working on recombinant antibodies as well as cli- cians involved with antibody-based therapies. As with other volumes of this series, we placed the main focus on providing detailed protocols describing procedures step-by-step. Moreover, each protocol supplies a troubleshooting guide containing detailed information on possible problems and hints for pot- tial solutions. Antibody technology is a subject of constant and rapid change. This volume, therefore, does not attempt to cover all possible current experimental approaches in the field. Rather, we present carefully selected protocols, written by competent authors who have successfully verified the particular method described. Given our own professional backgrounds and interest in oncology, we chose to conc- trate chiefly on therapeutic agents for cancer patients. Methods and Protocols Buch (fremdspr.) Bücher>Fremdsprachige Bücher>Englische Bücher, Springer Verlag GmbH

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Recombinant Antibodies for Cancer Therapy: Methods and Protocols - Martin Welschof#Jürgen Krauss
Livre non disponible
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Martin Welschof#Jürgen Krauss:

Recombinant Antibodies for Cancer Therapy: Methods and Protocols - nouveau livre

ISBN: 9780896039186

ID: 2f15f6cc6393e64446234d3ddaa380e4

Methods and Protocols Since the advent of hybridoma technology more than two decades ago, numerous antibodies have entered the clinical setting as potent therapeutic agents. Their repeated application in humans, however, is limited by the development of human antimouse antibodies (HAMA) in the recipient, leading to allergic re- tions against the foreign murine protein and rapid neutralization. To circumvent these limitations many new antibodies have recently been tailored through recombinant antibody technology. The initial clinical data show encouraging results, thus demonstrating the potential of these new therapeutic agents. The purpose of Recombinant Antibodies for Cancer Therapy is to present a collection of detailed protocols in recombinant antibody technology. It is pri- rily addressed to scientists working on recombinant antibodies as well as cli- cians involved with antibody-based therapies. As with other volumes of this series, we placed the main focus on providing detailed protocols describing procedures step-by-step. Moreover, each protocol supplies a troubleshooting guide containing detailed information on possible problems and hints for pot- tial solutions. Antibody technology is a subject of constant and rapid change. This volume, therefore, does not attempt to cover all possible current experimental approaches in the field. Rather, we present carefully selected protocols, written by competent authors who have successfully verified the particular method described. Given our own professional backgrounds and interest in oncology, we chose to conc- trate chiefly on therapeutic agents for cancer patients. Bücher / Fremdsprachige Bücher / Englische Bücher 978-0-89603-918-6, Springer

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Recombinant Antibodies for Cancer Therapy: Methods and Protocols - Martin Welschof#Jürgen Krauss
Livre non disponible
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Martin Welschof#Jürgen Krauss:
Recombinant Antibodies for Cancer Therapy: Methods and Protocols - nouveau livre

ISBN: 9780896039186

ID: 574819739

Since the advent of hybridoma technology more than two decades ago, numerous antibodies have entered the clinical setting as potent therapeutic agents. Their repeated application in humans, however, is limited by the development of human antimouse antibodies (HAMA) in the recipient, leading to allergic re- tions against the foreign murine protein and rapid neutralization. To circumvent these limitations many new antibodies have recently been tailored through recombinant antibody technology. The initial clinical data show encouraging results, thus demonstrating the potential of these new therapeutic agents. The purpose of Recombinant Antibodies for Cancer Therapy is to present a collection of detailed protocols in recombinant antibody technology. It is pri- rily addressed to scientists working on recombinant antibodies as well as cli- cians involved with antibody-based therapies. As with other volumes of this series, we placed the main focus on providing detailed protocols describing procedures step-by-step. Moreover, each protocol supplies a troubleshooting guide containing detailed information on possible problems and hints for pot- tial solutions. Antibody technology is a subject of constant and rapid change. This volume, therefore, does not attempt to cover all possible current experimental approaches in the field. Rather, we present carefully selected protocols, written by competent authors who have successfully verified the particular method described. Given our own professional backgrounds and interest in oncology, we chose to conc- trate chiefly on therapeutic agents for cancer patients. Methods and Protocols Buch (fremdspr.) Bücher>Fremdsprachige Bücher>Englische Bücher, Springer

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Recombinant Antibodies For Cancer Therapy: Methods And Protocols
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Recombinant Antibodies For Cancer Therapy: Methods And Protocols - nouveau livre

ISBN: 9780896039186

ID: 978089603918

In Recombinant Antibodies for Cancer Therapy: Methods and Protocols, Martin Welschoff and Jürgen Krauss present a collection of carefully selected protocols for the design, construction, and characterization of novel anticancer therapeutics based on recombinant antibody technology. These readily reproducible methods include coverage of hybridoma-derived recombinant antibodies, recombinant antibody fragments from phagemid-displayed antibody repertoires, antibody fragments with additional properties, and large-scale production of recombinant antibodies for clinical applications. Concise review articles also survey the current status of recombinant antibodies in cancer therapy, as well as the generation of antibody molecules through antibody engineering. Books, Health and Well Being, Recombinant Antibodies For Cancer Therapy: Methods And Protocols Books>Health and Well Being, Humana Press

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Recombinant Antibodies for Cancer Therapy - Martin Welschof; Jurgen Krauss
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Martin Welschof; Jurgen Krauss:
Recombinant Antibodies for Cancer Therapy - edition reliée, livre de poche

2002, ISBN: 9780896039186

ID: 4405478

Hardcover, Buch, [PU: Humana Press Inc.]

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Détails sur le livre
Recombinant Antibodies for Cancer Therapy: Methods and Protocols
Auteur:

Welschof, Martin Krauss, Jurgen Krauss, Jrgen

Titre:

Recombinant Antibodies for Cancer Therapy: Methods and Protocols

ISBN:

9780896039186

In Recombinant Antibodies for Cancer Therapy: Methods and Protocols, Martin Welschoff and JA1/4rgen Krauss present a collection of carefully selected protocols for the design, construction, and characterization of novel anticancer therapeutics based on recombinant antibody technology. These readily reproducible methods include coverage of hybridoma-derived recombinant antibodies, recombinant antibody fragments from phagemid-displayed antibody repertoires, antibody fragments with additional properties, and large-scale production of recombinant antibodies for clinical applications. Concise review articles also survey the current status of recombinant antibodies in cancer therapy, as well as the generation of antibody molecules through antibody engineering.

Informations détaillées sur le livre - Recombinant Antibodies for Cancer Therapy: Methods and Protocols


EAN (ISBN-13): 9780896039186
ISBN (ISBN-10): 0896039188
Version reliée
Date de parution: 2002
Editeur: SPRINGER VERLAG GMBH
496 Pages
Poids: 0,921 kg
Langue: eng/Englisch

Livre dans la base de données depuis 28.02.2007 10:42:20
Livre trouvé récemment le 14.11.2016 04:25:48
ISBN/EAN: 9780896039186

ISBN - Autres types d'écriture:
0-89603-918-8, 978-0-89603-918-6

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