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Much work over the last two decades has firmly established that loss of cell cycle checkpoint regulation, and resultant unabated cellular proliferation, is an inherent characteristic of c… Plus…

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Paperback, [PU: Humana Press Inc.], This loss may occur through aberration in any single component involved in signal transduction pathways that orchestrate checkpoint regulation, which m… Plus…

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Checkpoint Controls and Targets in Cancer Therapy - nouveau livre

2012, ISBN: 1617796352

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Informations détaillées sur le livre - Checkpoint Controls and Targets in Cancer Therapy by Zahid H. Siddik Paperback | Indigo Chapters


EAN (ISBN-13): 9781617796357
ISBN (ISBN-10): 1617796352
Livre de poche
Date de parution: 2012
Editeur: Zahid H. Siddik
288 Pages
Poids: 0,544 kg
Langue: Englisch

Livre dans la base de données depuis 2008-07-30T15:40:12+02:00 (Paris)
Page de détail modifiée en dernier sur 2022-10-07T19:29:45+02:00 (Paris)
ISBN/EAN: 1617796352

ISBN - Autres types d'écriture:
1-61779-635-2, 978-1-61779-635-7
Autres types d'écriture et termes associés:
Titre du livre: checkpoint


Données de l'éditeur

Auteur: Zahid H. Siddik
Titre: Cancer Drug Discovery and Development; Checkpoint Controls and Targets in Cancer Therapy
Editeur: Humana; Humana Press
274 Pages
Date de parution: 2012-03-07
Totowa; NJ; US
Imprimé / Fabriqué en
Poids: 0,552 kg
Langue: Anglais
160,49 € (DE)
164,99 € (AT)
177,00 CHF (CH)
POD
XIV, 274 p. 43 illus., 13 illus. in color.

BC; Cancer Research; Hardcover, Softcover / Medizin/Nichtklinische Fächer; Onkologie; Verstehen; BRCA; DNA; cancer; cancer research; cancer therapy; cell; cell death; leukemia; lymphoma; ovarian cancer; research; resistance; tumor; Oncology; Pharmacology/Toxicology; Cancer Biology; Oncology; Pharmacology; Pharmakologie; BB

Part I: Circuitry of Checkpoint Response Chapter 1 G1/S Checkpoint in Normal and Cancer Cells (Bartek J, Copenhagen, Denmark) Chapter 2 S-Phase Checkpoint (Bunz F, Baltimore, MD) Chapter 3 G2/M Checkpoint (Stark GR, Cleveland, OH OR Lukas J, Copenhagen, Denmark) Chapter 4 Mitotic Spindle Checkpoint (Hoffman I, Heidelberg, Germany) Chapter 5 ATM/Chk2 and ATR/Chk1 Pathways (Dunphy WG, Pasadena, CA OR Kastan MB, Memphis, TN) Chapter 7 INK/CIP inhibitor family members (Xiong Y, Chapel Hill, NC OR Rudolph KL, Hannover, Germany) Chapter 8 Centrosome in Checkpoint Response (Muschel RJ, Philadelphia, PA OR Kramer A, Heidelberg, Germany) Chapter 9 14-3-3 Family in Checkpoint Response (Lee M-H, Houston, TX OR Hermeking H, Munich, Germany) Chapter 10 BRCA1/2 in Checkpoint (Deng CX, Bethesda, MD OR Boulton SJ, South Mimms, UK) Chapter 11 Regulation of Checkpoint Response by CDC25 (Ducommun R, Toulouse, France) Chapter 12 DNA Damage Recognition in Checkpoint Response (Marini F, Milano, Italy) Part II: Checkpoint Response and the Aetiology of Cancer Chapter 13 Checkpoint Response and Cancer (Nakanishi M, Nagoya, Japan OR Mollinari M, Milan, Italy) Chapter 14 G1-Phase Cyclins and Cancer (Hinds PW, Boston, MA OR Keyomarsi K, Houston, TX) Chapter 15 Tumor Suppressor p53 and Cancer (El-Deiry WS, Philadelphia, PA OR Zambetti GP, Memphis, TN) Chapter 16 Rb dysfunction and Cancer (Giordano A, Philadelphia, PA) Chapter 17 Chk2 Status in Cancer (Nevanlinna H, Helsinki, Finland) Chapter 18 BRCA1/2 in Cancer (Borgen PI, New York, NY) Part III: Targeting Checkpoint Response in Cancer Therapy Chapter 19 Checkpoint Response and the Balance Between Cell Survival and Cell Death (Kaina B, Mainz, Germany OR Saito T, Tochigi, Japan) Chapter 20 Targeting p53 for checkpoint activation (Eastman A, Lebanon, NH OR Giardina C, Storrs, CT Chapter 21 Targeting Checkpoint Kinases with Small molecule inhibitors (Shapiro GI, Boston, MA OR Toogood PL, Ann Arbor, MI) Chapter 22 p21-Dependent Checkpoint Response and Therapy (Siddik ZH, Houston, TX) Chapter 23 p27 Upregulation as a Target for Therapy-Mediated Cell Death (Bast R, Houston, TX OR Malek NP, Hannover, Germany) Chapter 24 Chk1/Chk2 as checkpoint targets (Zhang H, Abbott Park, IL OR Grant S, Richmond) Chapter 25 Mitotic Spindle Checkpoint as a Target (Taylor SS, Manchester, UK OR Jackson JR, Collegeville, PA) Chapter 26 Targeting Cdc25 in cancer therapy (Rudolph J, Durham, NC)

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