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Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics - Patrick Augustijns; Marcus Brewster
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Patrick Augustijns; Marcus Brewster:

Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics - edition reliée, livre de poche

2007, ISBN: 9780387691497

Buch, Hardcover, 2007 ed. Solvent systems are integral to drug development and pharmaceutical technology. This single topic encompasses numerous allied subjects running the gamut from rec… Plus…

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Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics - edition reliée, livre de poche

2007, ISBN: 0387691499

[EAN: 9780387691497], Nouveau livre, [SC: 15.0], [PU: Springer New York], AUGUSTIJNS BIOPHARMACEUTICS BREWSTER PHARMACEUTICS SOLVENT SYSTEMS SELECTION MEDIZIN PHARMAZIE PHARMAKOLOGIE PHAR… Plus…

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Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics - Livres de poche

2007

ISBN: 9780387691497

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Augustijns, Patrick (Editor)/ Brewster, Marcus E. (Editor):
Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics (Biotechnology: Pharmaceutical Aspects) (Biotechnology: Pharmaceutical Aspects) - edition reliée, livre de poche

2007, ISBN: 9780387691497

Amer Assn of Pharmaceutical, 2007. Hardcover. New. 1st edition. 459 pages. 10.00x7.00x1.00 inches., Amer Assn of Pharmaceutical, 2007, 6

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Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics - Brewster, Marcus (Herausgeber); Augustijns, Patrick (Herausgeber)
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Brewster, Marcus (Herausgeber); Augustijns, Patrick (Herausgeber):
Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics - edition reliée, livre de poche

2007, ISBN: 0387691499

2007 Gebundene Ausgabe Compiler und Übersetzer, mit Schutzumschlag 11, [PU:Springer New York; Springer US, New York, N.Y.]

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Détails sur le livre
Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics

Solvent systems are integral to drug development and pharmaceutical technology. This single topic encompasses numerous allied subjects running the gamut from recrystallization solvents to biorelevant media. The goal of this contribution to the AAPS Biotechnology: Pharmaceutical Aspects series is to generate both a practical handbook as well as a reference allowing the reader to make effective decisions concerning the use of solvents and solvent systems. To this end, the monograph was created by inviting recognized experts from a number of fields to author relevant sections. Specifically, 15 chapters have been designed covering the theoretical background of solubility, the effect of ionic equilibria and pH on solubilization, the use of solvents to effect drug substance crystallization and polymorph selection, the use of solvent systems in high throughput screening and early discovery, solvent use in preformulation, the use of solvents in bio-relevant dissolution and permeation experiments, solvents and their use as toxicology vehicles, solubilizing media and excipients in oral and parenteral formulation development, specialized vehicles for protein formulation and solvent systems for topical and pulmonary drug administration. The chapters are organized such that useful decision trees are included together with the scientific underpinning for their application. In addition, trends in the use of solvent systems and a balance of current views make this monograph useful to both the novice and experienced researcher and to scientists at all developmental stages from early discovery to late pharmaceutical operations.

Informations détaillées sur le livre - Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics


EAN (ISBN-13): 9780387691497
ISBN (ISBN-10): 0387691499
Version reliée
Livre de poche
Date de parution: 2007
Editeur: Springer New York
459 Pages
Poids: 1,007 kg
Langue: eng/Englisch

Livre dans la base de données depuis 2008-01-18T01:10:44+01:00 (Paris)
Page de détail modifiée en dernier sur 2023-12-17T21:07:05+01:00 (Paris)
ISBN/EAN: 0387691499

ISBN - Autres types d'écriture:
0-387-69149-9, 978-0-387-69149-7
Autres types d'écriture et termes associés:
Auteur du livre: augustijn, polymorph, marcus, brewster, augusti
Titre du livre: biotechnology pharmaceutical aspects, the selection, system, systems art


Données de l'éditeur

Auteur: Patrick Augustijns; Marcus Brewster
Titre: Biotechnology: Pharmaceutical Aspects; Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics
Editeur: Springer; Springer US
462 Pages
Date de parution: 2007-06-08
New York; NY; US
Imprimé / Fabriqué en
Poids: 1,201 kg
Langue: Anglais
235,39 € (DE)
241,99 € (AT)
260,00 CHF (CH)
POD
X, 462 p. 119 illus., 9 illus. in color.

BB; Pharmacology/Toxicology; Hardcover, Softcover / Medizin/Pharmazie; Pharmakologie; Verstehen; Augustijns; Biopharmaceutics; Brewster; Pharmaceutics; Solvent; Systems; selection; Programming Languages, Compilers, Interpreters; Pharmacology; Compilers and Interpreters; Compiler und Übersetzer; BC; EA

Principles of Solubility.- Ionic Equilibria and the pH Dependence of Solubility.- Solvent Systems for Crystallization and Polymorph Selection.- Solubility Issues in Early Discovery and HTS.- Practical Aspects of Solubility Determination in Pharmaceutical Preformulation.- Biorelevant Dissolution Media.- Selection of Solvent Systems for Membrane-, Cell- and Tissue-Based Permeability Assessment.- The Use of Solubilizing Excipients and Approaches to Generate Toxicology Vehicles for Contemporary Drug Pipelines.- Solubilizing Vehicles for Oral Formulation Development.- Solubilizing Systems for Parenteral Formulation Development—Small Molecules.- Aqueous Solubilizing Systems for Parenteral Formulation Development—Proteins.- Non-Aqueous Systems for Formulation Development—Proteins.- Pharmaceutical Solvents as Vehicles for Topical Dosage Forms.- Pharmaceutical Solvents for Pulmonary Drug Delivery.

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