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Modulation Of Protein Stability In Cancer Therapy
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Modulation Of Protein Stability In Cancer Therapy - nouveau livre

ISBN: 9780387691435

ID: 5933000

Over the past two decades, there has been a tremendous increase in our understa- ing of ubiquitination and proteasome degradation. As the editors, we thank Springer Publishing for allowing us to organize this collection of reviews on the ubiquit- proteasome system, oncogenesis, and cancer therapy. We asked our colleagues, who are experts in the field, to provide an overview of their research. Over the past two decades, there has been a tremendous increase in our understa- ing of ubiquitination and proteasome degradation. As the editors, we thank Springer Publishing for allowing us to organize this collection of reviews on the ubiquit- proteasome system, oncogenesis, and cancer therapy. We asked our colleagues, who are experts in the field, to provide an overview of their research and recent progress. Each chapter covers a broad range of topics that include defects in ubiquitination identified in specific tumors to new directions to treat cancer. In the Introduction, Rati Verma gives the background of our current understanding of the proteasome. A general overview of ubiquitin ligases and cancer is provided by Angelika Burger and Arun Seth. Patricia McChesney and Gary Kupfer discuss the role of the Fanconi anemia/BRCA1 pathways in breast cancer and potential targets for therapy. Defects in the tumor suppressor, von Hippel-Lindau E3 ligase, and the role of this protein complex are discussed by William Kim and William Kaelin. Kyung-bo Kim and colleagues describe the development of novel proteasome inhibitors to treat cancer patients. Progress in our understanding of deubiquitinating enzymes is summarized by Massimo Loda and his colleagues. Finally, Agustin Rodriguez-Gonzalez and Kathleen Sakamoto discuss an approach to recruit cancer-causing proteins to ub- uitin ligases through a chimeric molecule known as protacs. Books, Medical~~Clinical & Internal Medicine~~Diseases & Disorders, Modulation Of Protein Stability In Cancer Therapy~~Book~~9780387691435, , , , , , , , , ,, [PU: Springer]

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Modulation of Protein Stability in Cancer Therapy - Springer
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Modulation of Protein Stability in Cancer Therapy - nouveau livre

ISBN: 9780387691435

ID: 6304eb8a9b0db10d1b662d4c26c7e050

This comprehensive monograph on the role of protein modulation in cancer therapeutics focuses on targeting molecules that regulate protein stability in a variety of tumors. Topics covered include ubiquitin ligases, deubiquitinating enzymes, and the proteasome. Over the past two decades, there has been a tremendous increase in our understa- ing of ubiquitination and proteasome degradation. As the editors, we thank Springer Publishing for allowing us to organize this collection of reviews on the ubiquit- proteasome system, oncogenesis, and cancer therapy. We asked our colleagues, who are experts in the field, to provide an overview of their research and recent progress. Each chapter covers a broad range of topics that include defects in ubiquitination identified in specific tumors to new directions to treat cancer. In the Introduction, Rati Verma gives the background of our current understanding of the proteasome. A general overview of ubiquitin ligases and cancer is provided by Angelika Burger and Arun Seth. Patricia McChesney and Gary Kupfer discuss the role of the Fanconi anemia/BRCA1 pathways in breast cancer and potential targets for therapy. Defects in the tumor suppressor, von Hippel Lindau E3 ligase, and the role of this protein complex are discussed by William Kim and William Kaelin. Kyung-bo Kim and colleagues describe the development of novel proteasome inhibitors to treat cancer patients. Progress in our understanding of deubiquitinating enzymes is summarized by Massimo Loda and his colleagues. Finally, Agustin Rodriguez-Gonzalez and Kathleen Sakamoto discuss an approach to recruit cancer-causing proteins to ub- uitin ligases through a chimeric molecule known as protacs. Bücher / Fremdsprachige Bücher / Englische Bücher 978-0-387-69143-5, Springer

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Modulation of Protein Stability in Cancer Therapy - Springer
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Springer:
Modulation of Protein Stability in Cancer Therapy - nouveau livre

ISBN: 9780387691435

ID: 499576917

Over the past two decades, there has been a tremendous increase in our understa- ing of ubiquitination and proteasome degradation. As the editors, we thank Springer Publishing for allowing us to organize this collection of reviews on the ubiquit- proteasome system, oncogenesis, and cancer therapy. We asked our colleagues, who are experts in the field, to provide an overview of their research and recent progress. Each chapter covers a broad range of topics that include defects in ubiquitination identified in specific tumors to new directions to treat cancer. In the Introduction, Rati Verma gives the background of our current understanding of the proteasome. A general overview of ubiquitin ligases and cancer is provided by Angelika Burger and Arun Seth. Patricia McChesney and Gary Kupfer discuss the role of the Fanconi anemia/BRCA1 pathways in breast cancer and potential targets for therapy. Defects in the tumor suppressor, von Hippel Lindau E3 ligase, and the role of this protein complex are discussed by William Kim and William Kaelin. Kyung-bo Kim and colleagues describe the development of novel proteasome inhibitors to treat cancer patients. Progress in our understanding of deubiquitinating enzymes is summarized by Massimo Loda and his colleagues. Finally, Agustin Rodriguez-Gonzalez and Kathleen Sakamoto discuss an approach to recruit cancer-causing proteins to ub- uitin ligases through a chimeric molecule known as protacs. This comprehensive monograph on the role of protein modulation in cancer therapeutics focuses on targeting molecules that regulate protein stability in a variety of tumors. Topics covered include ubiquitin ligases, deubiquitinating enzymes, and the proteasome. Buch (fremdspr.) Bücher>Fremdsprachige Bücher>Englische Bücher, Springer

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Modulation of Protein Stability in Cancer Therapy - Kathleen Sakamoto
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Kathleen Sakamoto:
Modulation of Protein Stability in Cancer Therapy - nouveau livre

4, ISBN: 9780387691435

[ED: Buch], [PU: Springer-Verlag GmbH], Neuware - Over the past two decades, there has been a tremendous increase in our understa- ing of ubiquitination and proteasome degradation. As the editors, we thank Springer Publishing for allowing us to organize this collection of reviews on the ubiquit- proteasome system, oncogenesis, and cancer therapy. We asked our colleagues, who are experts in the field, to provide an overview of their research and recent progress. Each chapter covers a broad range of topics that include defects in ubiquitination identified in specific tumors to new directions to treat cancer. In the Introduction, Rati Verma gives the background of our current understanding of the proteasome. A general overview of ubiquitin ligases and cancer is provided by Angelika Burger and Arun Seth. Patricia McChesney and Gary Kupfer discuss the role of the Fanconi anemia/BRCA1 pathways in breast cancer and potential targets for therapy. Defects in the tumor suppressor, von Hippel-Lindau E3 ligase, and the role of this protein complex are discussed by William Kim and William Kaelin. Kyung-bo Kim and colleagues describe the development of novel proteasome inhibitors to treat cancer patients. Progress in our understanding of deubiquitinating enzymes is summarized by Massimo Loda and his colleagues. Finally, Agustin Rodriguez-Gonzalez and Kathleen Sakamoto discuss an approach to recruit cancer-causing proteins to ub- uitin ligases through a chimeric molecule known as protacs., [SC: 0.00]

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Modulation of Protein Stability in Cancer Therapy - Sakamoto, Kathleen (EDT)/ Rubin, Eric (EDT)
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Sakamoto, Kathleen (EDT)/ Rubin, Eric (EDT):
Modulation of Protein Stability in Cancer Therapy - nouveau livre

ISBN: 038769143X

ID: 038769143X

[PU: Springer]

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Détails sur le livre
Modulation of Protein Stability in Cancer Therapy
Auteur:

Kathleen Sakamoto

Titre:

Modulation of Protein Stability in Cancer Therapy

ISBN:

038769143X

The book that Sakamoto proposes along with Eric Ruben will be a comprehensive monograph on the role of protein modulation in cancer therapeutics; it will focus on targeting molecules that regulate protein stability in a variety of tumors.

Informations détaillées sur le livre - Modulation of Protein Stability in Cancer Therapy


EAN (ISBN-13): 9780387691435
ISBN (ISBN-10): 038769143X
Version reliée
Date de parution: 2009
Editeur: Springer-Verlag GmbH
165 Pages
Poids: 0,425 kg
Langue: eng/Englisch

Livre dans la base de données depuis 23.03.2007 07:10:00
Livre trouvé récemment le 18.09.2016 21:08:44
ISBN/EAN: 038769143X

ISBN - Autres types d'écriture:
0-387-69143-X, 978-0-387-69143-5

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